"Glycans are the most complex and
structurally diversified molecules involved in communication between cells and
interactions between infectious organisms and their host, such as in bacterial
infections in humans. Identification of their biological functions and role in
diseases will provide unique opportunities to develop new diagnostic and
therapeutic approaches." |
|
Dr. Jean-Robert Brisson, Research Director, Glycobiology
Program |
Glycobiology, an emerging field of science,
combines the disciplines of both carbohydrate biochemistry and molecular
biology to study and understand the structure, biosynthesis and
biological function of glycans. Research in the
Glycobiology Program at NRC-IBS is aimed at development of carbohydrate-based
therapeutics for infectious and neurodegenerative diseases. Research activities
also include the characterization and development of carbohydrate processing
enzymes for therapeutic and industrial applications. The Program develops and
applies core technologies for molecular analyses of carbohydrates, along with
genomics and proteomics support to identify the biological function of
carbohydrates. Research activities support projects in the Immunobiology and
Neurobiology Programs.
The Glycobiology Program comprises five distinct
groups: Glycoanalysis,
Genomics & Proteomics,
Glycosidases,
Eukaryotic Glycobiology,
Glycosyltranferases and Neuroglycomics |