Mass Spectrometry

Mass spectrometry (MS) is widely used to characterize a variety of chemicals and biomolecules, such as proteins and peptides in proteomics studies and metabolites in drug discovery studies. When mass spectrometry and liquid chromatography are coupled, complex mixtures of numerous compounds may be analyzed to provide structural information in a single step. The high sensitivity of mass spectrometers makes possible the analysis of trace amount of samples.

The Mass Spectrometry Facility provides high resolution mass spectrometry (HR-MS) service. The laboratory is equipped with a state-of-the-art quadrupole time-of-flight (Q-ToF) mass spectrometer. The mass spectrometer may be used independently or in-line with a liquid chromatographic system. The accurate mass determinations for small molecules, peptides and proteins as well as LC-MS/MS experiments for proteomics are the frequent use of the instrument. The softwares support the analysis of biomolecules such as proteins, peptides, oligonucleotides, and carbohydrate as well as other organic molecules such as metabolites.