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Randomized Controlled Trials - September 2005

Within the Randomized Controlled Trials program, the review committee has the discretion to assign an "Under Continuing Review (UCR)" rating to those applications where there is/are minor concern(s), or additional information/clarification is required to complete the review process. Following the peer review meeting, the relevant applicants are asked to respond to specific questions, which are subsequently reviewed and assessed by the committee on an ad-hoc basis. Due to this process, announcement of all the successful grants in this program is delayed. Results will be posted as soon as they become available.

Name/Institution/Title Co-applicants Term (years)
1st Year amount Total Amount approved
KOVACS, Michael J.
London Health Sciences Centre
A double blind randomized control trial of post-operative low molecular weight heparin bridging therapy versus placebo bridging therapy for patients who are at high risk for arterial thromboembolism*
 
Rodger, M.A., Anderson, D.R., Wells, P.S., Kearon, C., Bates, S.M., Kahn, S.R., Solymoss, S., Shulman, S., Blostein, M.D. 5 $537,378 $2,312,255
KUMAR, Deepali
University Health Network (Toronto)
Immunogenicity of pneumococcal vaccine in liver transplant recipients
 
Humar, A., McGeer,A.J.,
Levy, G.A.
  3 $128,560 $320,776
MALTAIS, François
Université Laval
Effects of a home-based vs hospital based outpatient pulmonary rehabilitation program in patients with COPD: A multicenter, randomized controlled trial*
 
Bourbeau, J., Baltzan, M., Perrault, H., Lacasse, Y., Shapiro, S., Penrod, J.R.   1 $280,470 $280,470
MEHTA, Shamir
McMaster University
Early versus delayed invasive strategies in patients with acute coronary syndromes*
 
Yusuf, S., Natarajan, M.K., Pogue, J.M., Lamy, A., Gafni, A.   3 $218,873 $457,767
MOLLOY, David W.
McMaster University
Multi-centre, blinded, randomized, controlled trial comparing different regimens of the antibiotics doxycycline and rifampin for treatment of Alzheimer's disease*
 
Lewis, D.L., Borrie, M.J., Patterson, C.J., Decoteau, W.E., Jarrett, P.G., Woo, T.K., Chivers, R., MacKnight, C.R., Rockwood, K., Heckman, G.A., Black, S.E., Guyatt, G.H. 3.5 $516,382 $1,867,141
MORILLO, Carlos A.
McMaster University
Benznidazole evaluation for interrupting trypanosomiasis pilot trial (BENEFIT)*
 
Yusuf, S., Connolly, S.J., Marin-Neto, S.J., Rassis Jr., A., Avezum, A., Sosa-Estani, S.A., Villar, J.C.   3 $322,430 (includes $9,313 for equipment) $866,435
SCHMIDT, Barbara K.
McMaster University
Efficacy and safety of targeting lower arterial oxygen saturations to reduce oxygen toxicity and oxidative stress in very preterm infants: The Canadian oxygen trial (COT)*
 
Roberts, R.S., Whyte, R.K., Asztalos, E.V., Shah, P., Solimano, A.J., Bairam, A., Seshia, M., Moddeman, D.M., Chiu, A., Roukema, H.W., Sauve, R.S., Rabi., J., Harrold, J.E., Clarke, M.C.W., Kumar, M., Peliowski.   5 $776,972 $3,884,860
SPENCE, John D.
John P. Robarts Research Institute
Effect of L-thyroxine on progression of carotid atherosclerosis in subclinical hypothyroidism
 
House, A.W., Edmonds, M.W., Parraga, G.   3 $156,431 $451,071
ZELKOWITZ, Phyllis
Sir Mortimer B. Davis Jewish General Hospital
A trial of a skills-based intervention to reduce maternal anxiety and improve developmental outcomes in very low birthweight infants*
Feeley, N., Papageorgiou, A.N., Lefebvre, F., Westreich, R., Dunkley, D.M., Shrier, I., Roseberger, Z., Steele, R.J., Stremler, R.L.   4 $106,659 (includes $5,350 for equipment) $338,472


* indicates a multicentre study


Created: 2006-03-30
Modified: 2006-03-30
Reviewed: 2006-03-30
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