AECL's head office, with over 1,500 employees, is located in the Sheridan Science and Technology Park in Mississauga, Ontario, 25 km west of Toronto.

Most of AECL's nuclear projects are managed and supported from this location, as are AECL's engineering, commercial operations, international sales and marketing, as well as nuclear services initiatives.

Sheridan Park employees develop, manufacture and test many of AECL's commercial products and provide commercial services to clients.

AECL Sheridan Park offers term positions to co-op students and has an active summer employment program.