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|
| RTECS® Number |
WS5600000 |
| Chemical Name |
Sulfuric acid |
| CAS Registry Number |
7664-93-9 |
| Last Updated |
200012 |
| Data Items Cited |
59 |
| Molecular Formula |
H2-O4-S |
| Molecular Weight |
98.08 |
| Wiswesser Line Notation |
H2 S-O4 |
| Compound Descriptor |
Agricultural Chemical
Tumorigen
Mutagen
Reproductive Effector
Human
Primary Irritant |
- Synonyms/Trade Names
- * Acide sulfurique
* Acido solforico
* Battery acid
* BOV
* Dihydrogen sulfate
* Dipping acid
* Electrolyte acid
* Mattling acid
* Oil of vitriol
* Schwefelsaeureloesungen
* Strong inorganic acid mists containing sulfuric acid
* Sulfuric acid
* Sulphuric acid
* Vitriol Brown Oil
* Zwavelzuuroplossingen
|
| Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Reaction Severity |
Reference |
|
Standard Draize test
|
Administration into the eye
|
Rodent - rabbit
|
250 ug
|
Severe
|
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946
|
|
Rinsed with water
|
Administration into the eye
|
Rodent - rabbit
|
5 mg/30S
|
Severe
|
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 23,281,1982
|
|
| Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Toxic Effects |
Reference |
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Human
|
3 mg/m3/24W
|
Musculoskeletal - changes in teeth and supporting structures
|
BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 18,63,1961
|
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Human
|
1 mg/m3/3H
|
Lungs, Thorax, or Respiration - other changes
|
INHTE5 Inhalation Toxicology. (Hemisphere Publishing Corp., c/o Taylor & Francis Inc., 1900 Frost Rd., Suite 101, Bristol, PA 19007) V.1- 1989- Volume(issue)/page/year: 9,731,1997
|
|
LDLo - Lowest published lethal dose
|
Unreported
|
Human - man
|
135 mg/kg
|
Details of toxic effects not reported other than lethal dose value
|
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970
|
|
LD50 - Lethal dose, 50 percent kill
|
Oral
|
Rodent - rat
|
2140 mg/kg
|
Details of toxic effects not reported other than lethal dose value
|
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
|
|
LC50 - Lethal concentration, 50 percent kill
|
Inhalation
|
Rodent - rat
|
510 mg/m3/2H
|
Details of toxic effects not reported other than lethal dose value
|
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,107,1982
|
|
LC50 - Lethal concentration, 50 percent kill
|
Inhalation
|
Rodent - mouse
|
320 mg/m3/2H
|
Details of toxic effects not reported other than lethal dose value
|
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,107,1982
|
|
LC50 - Lethal concentration, 50 percent kill
|
Inhalation
|
Rodent - guinea pig
|
18 mg/m3
|
Lungs, Thorax, or Respiration - other changes
|
MELAAD Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122 Milan, Italy) V.16- 1925- Volume(issue)/page/year: 45,590,1954
|
|
| OTHER MULTIPLE DOSE TOXICITY DATA |
| Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Toxic Effects |
Reference |
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rat
|
784 ug/m3/24H/84D-C
|
Behavioral - muscle contraction or spasticity
Kidney, Ureter, Bladder - other changes in urine composition
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
|
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 38(3),6,1973
|
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Mammal - dog
|
900 ug/m3/21H/89W-I
|
Cardiac - changes in heart weight
Lungs, Thorax, or Respiration - other changes
Lungs, Thorax, or Respiration - changes in lung weight
|
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 26,16,1973
|
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Primate - monkey
|
2 mg/m3/23H/78W-I
|
Lungs, Thorax, or Respiration - other changes
|
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 27,16,1973
|
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - guinea pig
|
30 mg/m3/7D-C
|
Lungs, Thorax, or Respiration - acute pulmonary edema
Related to Chronic Data - death
|
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 3,521,1977
|
|
| Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Sex/Duration |
Toxic Effects |
Reference |
|
TCLo - Lowest published toxic concentration
|
Inhalation
|
Rodent - rabbit
|
20 mg/m3/7H
|
female 6-18 day(s) after conception
|
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
|
JEHSDH Journal of Environmental Science and Health, Part C: Environmental Health Sciences. New York, NY) V.13, 1978-79. Volume(issue)/page/year: 13,251,1979
|
|
| Type of Test |
Route of Exposure |
Species Observed |
Dose Data |
Reference |
|
Cytogenetic analysis
|
|
Rodent - hamster
Ovary
|
4 mmol/L
|
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 225,55,1989
|
|
|
|
|
ACGIH TLV-Suspected human carcinogen
|
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1999
|
|
ACGIH TLV-STEL 3 mg/m3
|
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1999
|
|
ACGIH TLV-TWA 1 mg/m3
|
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1999
|
|
IARC Cancer Review:Human Sufficient Evidence
|
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,41,1992
|
|
IARC Cancer Review:Group 1
|
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,41,1992
|
|
TOXICOLOGY REVIEW
|
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 10,35,1975
|
|
TOXICOLOGY REVIEW
|
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 39,299,1978
|
|
| U.S. STANDARDS AND REGULATIONS |
- EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
- FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
- MSHA STANDARD-air:TWA 1 mg/m3
- DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,239,1971
- OSHA PEL (Gen Indu):8H TWA 1 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994
- OSHA PEL (Construc):8H TWA 1 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994
- OSHA PEL (Shipyard):8H TWA 1 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993
- OSHA PEL (Fed Cont):8H TWA 1 mg/m3
- CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994
|
| OCCUPATIONAL EXPOSURE LIMITS |
- OEL-ARAB Republic of Egypt: TWA 1 mg/m3, JAN1993
- OEL-AUSTRALIA: TWA 1 mg/m3, JAN1993
- OEL-AUSTRIA: MAK 1 mg/m3, JAN1999
- OEL-BELGIUM: TWA 1 mg/m3, STEL 3 mg/m3, JAN1993
- OEL-DENMARK: TWA 1 mg/m3, JAN1999
- OEL-FINLAND: TWA 1 mg/m3, STEL 3 mg/m3, Skin, JAN1999
- OEL-FRANCE: VME 1 mg/m3, VLE 3 mg/m3, JAN1999
- OEL-GERMANY: MAK 1 mg/m3, JAN1999
- OEL-HUNGARY: STEL 1 mg/m3, JAN1993
- OEL-JAPAN: OEL 1 mg/m3, JAN1999
- OEL-THE NETHERLANDS: MAC-TGG 1 mg/m3, JAN1999
- OEL-NORWAY: TWA 1 mg/m3, JAN1999
- OEL-POLAND: MAC(TWA) 1 mg/m3, MAC(STEL) 3 mg/m3, JAN1999
- OEL-RUSSIA: STEL 1 mg/m3, Skin, JAN1993
- OEL-SWEDEN: NGV 1 mg/m3, TKV 3 mg/m3, JAN1999
- OEL-SWITZERLAND: MAK-W 1 mg/m3, KZG-W 2 mg/m3, JAN1999
- OEL-THAILAND: TWA 1 mg/m3, JAN1993
- OEL-TURKEY: TWA 1 mg/m3, JAN1993
- OEL-UNITED KINGDOM: TWA 1 mg/m3, SEP2000
- OEL IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV;
- OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
|
| NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA |
- NIOSH Recommended Exposure Level (Rel)
- NIOSH REL TO SULFURIC ACID-air:10H TWA 1 mg/m3
- Reference
- NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992
- NIOSH Occupational Exposure Survey Data
-
|
- EPA TSCA Section 8(b) CHEMICAL INVENTORY
- EPA TSCA Section 8(d) unpublished health/safety studies
- EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9247;8EHQ-0892-9248
- EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
- NIOSH Analytical Method, 1994: Acids, inorganic, 7903
- NTP 9th Report on Carcinogens, 2000:Known to be human carcinogen
- OSHA ANALYTICAL METHOD #ID-113
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©2001 Canadian Centre for Occupational Health & Safety 