Existing Substances Evaluation: DSL Categorization and Screening Pilot Project

Screening Assessment Pilot Project

A Pilot Project for the screening assessment phase was initiated by Environment Canada and Health Canada. This project identified 123 substances which were anticipated to meet the categorization criteria of 1) persistent and/or bioaccumulative and inherently toxic to non-human organisms or 2) having a high potential for exposure to Canadians.

The objectives of the pilot project are related to both process and scientific aspects of the program. Specifically, the objectives are to:

to refine the screening assessment process;
to develop and adopt tools and approaches for screening assessments;
to develop approaches for setting priorities for screening assessments;
to engage stakeholders on new approaches for screening assessments and priority-setting.

Of the list of 123 substances, 93 substances, categorized as persistent and/or bioaccumulative and inherently toxic to non-human organisms (environment), were proposed by a Technical Advisory Group of Environment Canada made up of experts from different interested parties including federal and provincial governments, industry participants, environmental non-government organizations, and academia.

The 30 substances initially selected by Health Canada were prioritized for inclusion in the pilot phase, based upon available data on their releases to the environment, levels in the environment, and/or amounts manufactured, imported or used in Canada.

The list of substances on the pilot list includes a range of chemical classes and uses of substances present on the Domestic Substances List. It therefore represents a sample of the type of substances which Environment Canada and Health Canada will categorize and assess in future years.

The approaches and processes for categorization of the DSL and subsequent screening assessment are being developed and refined during the pilot phase. Consideration will be given to the concerns of other government departments, stakeholders and other interest groups, and opportunities will be provided to comment on the categorization decisions and the screening assessments. There is provision for public comment on the results of the screening assessments conducted under Section 74 of CEPA, 1999.

Environment Canada published a notice under Section 71 of CEPA, 1999 in the Canada Gazette and sent this questionnaire to approximately 4,500 Canadian manufacturers or importers of the 123 substances requesting information on quantities manufactured, imported, exported, used or sold; industrial and potential consumer use patterns; concentrations in products; and unpublished persistence, bioaccumulation, toxicity and exposure data.

A comprehensive collection of information on Environment Canada's Screening Assessment Pilot Project appears on the Existing Substances Program CD-ROM. To obtain a copy of the most recent CD, please send a request to the following address: ESB.DSE@ec.gc.ca.

List of Pilot Project Substances

1. Substances in the class of antioxidants:

CAS RN	Name
93-46-9	1,4-Benzenediamine, N,N'-di-2-naphthalenyl-
96-69-5	Phenol, 4,4'-thiobis[2-(1,1-dimethylethyl)-5-methyl-
119-47-1	Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)- 4-methyl-
732-26-3	Phenol, 2,4,6-tris(1,1-dimethylethyl)-
991-84-4	Phenol, 4-[[4,6-bis(octylthio)-1,3,5-triazin-2-yl] amino]-2,6-bis(1,1-dimethylethyl)-
10081-67-1	Benzenamine, 4-(1-methyl-1-phenylethyl)-N-[4-(1- methyl-1-phenylethyl)phenyl]-
15721-78-5	Benzenamine, 4-(1,1,3,3-tetramethylbutyl)-N-[4- (1,1,3,3-tetramethylbutyl)phenyl]-

2. Substances in the class of brominated substances:

CAS RN	Name
79-94-7	Phenol, 4,4'-(1-methylethylidene)bis[2,6-dibromo-
87-84-3	Cyclohexane, 1,2,3,4,5-pentabromo-6-chloro-
608-71-9	Phenol, pentabromo-
1163-19-5	Benzene, 1,1'-oxybis[2,3,4,5,6-pentabromo-
3194-55-6	Cyclododecane, 1,2,5,6,9,10-hexabromo-
4162-45-2	Ethanol, 2,2 -[(1-methylethylidene)bis[(2,6-dibromo- 4,1-phenylene)oxy]]bis-
25327-89-3	Benzene, 1,1 -(1-methylethylidene)bis[3,5-dibromo- 4-(2-propenyloxy)-
30554-72-4	Cyclohexane, tetrabromodichloro-
30554-73-5	Cyclohexane, tribromotrichloro-
32534-81-9	Benzene, 1,1'-oxybis-, pentabromo deriv.
32536-52-0	Benzene, 1,1'-oxybis-, octabromo deriv.
32588-76-4	1H-Isoindole-1,3(2H)-dione, 2,2'-(1,2-ethanediyl)bis[4,5,6,7-tetrabromo-
36483-60-0	Benzene, 1,1'-oxybis-, hexabromo deriv.
37853-59-1	Benzene, 1,1'-[1,2-ethanediylbis(oxy)]bis[2,4,6- tribromo-
40088-47-9	Tetrabromodiphenyl ether
63936-56-1	Benzene, pentabromo(tetrabromophenoxy)-
68928-80-3	Benzene, 1,1'-oxybis-, heptabromo deriv.

3. Substances in the class of chlorinated substances:

CAS RN	Name
58-39-9	1-Piperazineethanol, 4-[3-(2-chloro-10H- phenothiazin-10-yl)propyl]-(Perphenazine)
58-89-9	Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1a,2a,3b,4a,5a,6b)-
67-72-1	Ethane, hexachloro-
70-30-4	Phenol, 2,2'-methylenebis[3,4,6-trichloro-
77-47-4	1,3-Cyclopentadiene, 1,2,3,4,5,5-hexachloro-
87-86-5	Phenol, pentachloro-
133-49-3	Benzenethiol, pentachloro-
1897-45-6	1,3-Benzenedicarbonitrile, 2,4,5,6-tetrachloro-
1912-24-9	1,3,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1- methylethyl)-(Atrazine)
3380-34-5	Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-
13560-89-9	1,4:7,10-Dimethanodibenzo[a,e]cyclooctene, 1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro- 1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-
66046-85-3	1H-Isoindole-1,3(2H)-dione, 2,2'-(1,6-hexanediyl)bis [4,5,6,7-tetrachloro-
73398-86-4	Pyridine, 4-(3-chloro-5-propylphenyl)-

4. Substances in the class of musks:

CAS RN	Name
77-54-3	1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8- tetramethyl-,acetate, [3R-(3a,3ab,6a,7b,8aa)]-
81-14-1	Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5- dinitrophenyl]-
145-39-1	Benzene, 1-(1,1-dimethylethyl)-3,4,5-trimethyl-2,6-dinitro-
1922-67-4	1H-Naphtho[2,3-c]pyran, 3,4,6,7,8,9-hexahydro- 4,6,6,9,9-pentamethyl-
21145-77-7	Ethanone,1-(5,6,7,8-tetrahydro-3,5,5,6,8,8- hexamethyl-2-naphthalenyl)-
58243-85-9	2-Naphthalenecarboxaldehyde,3-ethyl-5,6,7,8- tetrahydro-5,5,8,8-tetramethyl-

5. Substances in the class of nitro substances:

CAS RN	Name
1582-09-8	Benzenamine, 2,6-dinitro-N,N-dipropyl-4- (trifluoromethyl)-

6. Substances used as pigments and dyes:

CAS RN	Name
85-83-6	2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl)azo]phenyl]azo]-
129-09-9	Anthra[2,1-d:6,5-d']bisthiazole-6,12-dione, 2,8-diphenyl-
130-20-1	5,9,14,18-Anthrazinetetrone, 7,16-dichloro-6,15-dihydro-
492-80-8	Benzenamine, 4,4'-carbonimidoylbis[N,N-dimethyl-
603-48-5	Benzenamine, 4,4',4''-methylidynetris[N,N-dimethyl-
980-26-7	Quino[2,3-b]acridine-7,14-dione,5,12-dichloro-2,9-dihydro-
1324-11-4	Dibenzo[b,def]chrysene-7,14-dione, dibromo-
3089-17-6	Quino[2,3-b]acridine-7,14-dione, 2,9-dichloro-5,12-dihydro-
3271-76-9	Anthra[2,1,9-mna]naphth[2,3-h]acridine-5,10,15(16H)-trione
6358-30-1	Diindolo[3,2-b:3',2'-m]triphenodioxazine, 8,18-dichloro- 5,15-diethyl-5,15-dihydro-
6408-72-6	9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy
10319-14-9	1H-Indene-1,3(2H)-dione, 2-(4-bromo-3-hydroxy-2- quinolinyl)-
15086-94-9	Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy-
25150-28-1	Propanenitrile, 3-[[4-[(6,7-dichloro-2-benzothiazolyl)azo] phenyl]ethylamino]-
29512-49-0	Spiro[isobenzofuran-1(3H),9 -[9H]xanthen]-3-one, 6 - (diethylamino)-3 -methyl-2 -(phenylamino)-
64086-95-9	9,10-Anthracenedione, 1-amino-2-bromo-4-[[4-[(1- methylethyl)amino]-6-phenyl-1,3,5-triazin-2-yl]amino]-

7. Substances in the class of phthalates substances:

CAS RN	Name
84-61-7	1,2-Benzenedicarboxylic acid, dicyclohexyl ester
84-76-4	1,2-Benzenedicarboxylic acid, dinonyl ester
119-06-2	1,2-Benzenedicarboxylic acid, ditridecyl ester
131-18-0	1,2-Benzenedicarboxylic acid, dipentyl ester
3648-20-2	1,2-Benzenedicarboxylic acid, diundecyl ester
27554-26-3	1,2-Benzenedicarboxylic acid, diisooctyl ester
28553-12-0	1,2-Benzenedicarboxylic acid, diisononyl ester

8. Miscellaneous substances:

CAS RN	Name
56-49-5	Benz[j]aceanthrylene, 1,2-dihydro-3-methyl-
57-97-6	Benz[a]anthracene, 7,12-dimethyl-
72-43-5	Benzene, 1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
76-60-8	Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-3-methyl-, S,S-dioxide
77-62-3	Phenol, 2,2'-methylenebis[4-methyl-6-(1-methylcyclohexyl)-
87-10-5	Benzamide, 3,5-dibromo-N-(4-bromophenyl)-2-hydroxy-
101-14-4	Benzenamine, 4,4'-methylenebis[2-chloro-
101-61-1	Benzenamine, 4,4'-methylenebis[N,N-dimethyl-
101-65-5	Carbamic acid, (methylenedi-4,1-phenylene)bis-, diphenyl ester
101-75-7	Benzenamine, N-phenyl-4-(phenylazo)-
603-35-0	Phosphine, triphenyl-
1222-05-5	Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
1446-61-3	1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1a,4ab,10aa)]-
3691-35-8	1H-Indene-1,3(2H)-dione, 2-[(4-chlorophenyl)phenylacetyl]-
3846-71-7	Phenol, 2-(2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylethyl)-
4979-32-2	2-Benzothiazolesulfenamide, N,N-dicyclohexyl-
5285-60-9	Benzenamine, 4,4'-methylenebis[N-(1-methylpropyl)-
6386-38-5	Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester
13171-00-1	Ethanone, 1-[6-(1,1-dimethylethyl)-2,3-dihydro-1,1-dimethyl-1H- inden-4-yl]-
23593-75-1	1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-
25973-55-1	Phenol, 2-(2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylpropyl)-
26140-60-3	Terphenyl
54079-53-7	Propanedinitrile, [[4-[[2-(4-cyclohexylphenoxy)ethyl]ethylamino]-2- methylphenyl]methylene]-
54827-17-7	[1,1'-Biphenyl]-4,4'-diamine, 3,3',5,5'-tetramethyl-
57082-24-3	Tricyclo[6.3.1.02,5]dodecan-1-ol, 4,4,8-trimethyl-, acetate, [1R-(1a,2a,5b,8b)]-
89347-09-1	1,3,4-Thiadiazole, 2,5-bis(tert-nonyldithio)-

9. Substances with potential for significant exposure to Canadians:

CAS RN	Name
51-28-5	Phenol, 2,4-dinitro (2,4-Dinitrophenol)
59-50-7	Phenol, 4-chloro-3-methyl- (4-Chloro-3-methylphenol)
67-56-1	Methanol
67-63-0	2-Propanol (Isopropyl alcohol)
67-64-1	2-Propanone (Acetone)
71-36-3	1-Butanol (n-Butyl alcohol)
74-85-1	Ethene (Ethylene)
75-35-4	Ethene, 1,1-dichloro-(1,1-Dichloroethylene)
78-87-5	Propane, 1,2-dichloro- (1,2-Dichloropropane)
78-93-3	2-Butanone (Methyl ethyl ketone)
79-92-5	Bicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene- (Camphene
91-20-3	Naphthalene
91-22-5	Quinoline
92-52-4	1,1'-Biphenyl (Diphenyl)
95-63-6	Benzene, 1,2,4-trimethyl-
100-41-4	Benzene, ethyl- (Ethyl benzene)
106-93-4	Ethane, 1,2-dibromo (Ethylene dibromide)
108-10-1	2-Pentanone, 4-methyl- (Methyl isobutyl ketone)
110-82-7	Cyclohexane
111-42-2	Ethanol, 2,2'-iminobis- and its salts (Diethanolamine and its salts)
111-46-6	Ethanol, 2,2'-oxybis- (Glycols or Diethylene glycol)
115-07-1	1-Propene (Propylene)
120-83-2	Phenol, 2,4-dichloro- (2,4-Dichlorophenol)
124-18-5	Decane
534-52-1	Phenol, 2-methyl-4,6-dinitro- (4,6-Dinitro-o-cresol)
1330-78-5	Phosphoric acid, tris(methylphenyl) ester (Tritolyl phosphate)
7647-01-0	Hydrochloric acid
7664-93-9	Sulfuric acid
7783-06-4	Hydrogen sulfide
10049-04-4	Chlorine oxide (Chlorine dioxide)

	\| What's New \| About Us \| Topics \| Publications \| Weather \| Home \|
	\| Help \| Search \| Canada Site \|
	The Green LaneTM, Environment Canada's World Wide Web site
		Important Notices