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Institute of Aboriginal Peoples' Health (IAPH)

Update on the Cardiovascular Complications of Diabetes Initiative & Notification of the Planned Request for Applications

Many of the complications of type I and type II diabetes are cardiovascular in nature (e.g., micro-vascular, macro-vascular). The burden of cardiovascular complications in diabetes among Canadians is growing at an alarming rate. The number of Aboriginal people, women, elderly and youth who are affected by diabetes and cardiovascular sequelae including heart attack, stroke, dementia, blindness, renal failure and limb loss is growing. Although diabetes is a well-known risk factor for cardiovascular disease, the exact biological mechanisms, social processes, and broader determinants underlying these complications or the optimal ways to prevent or manage them are still in doubt. Our current understanding of the interactions between the diabetic state and other risk factors for cardiovascular diseases is poor. Canada has already contributed much to this area of research investigation. Through Canadian leadership, we can improve our understanding of cardiovascular complications of diabetes and the ways in which affected Canadians can be treated and managed more effectively.

Planned Request for Applications - December 2005

The partners listed below are planning to launch a Request for Applications (RFA) program in December 2005 focused on important research themes targeting the area of cardiovascular complications of diabetes. The specific areas of focus for this RFA are currently being developed and will be informed by the outcomes of a New Frontiers Program (NFP) workshop (see below for details).

Research activity is required at the interface between the diabetes and cardiovascular communities, drawing on new disciplines and approaches and is the focus of the planned RFA. Depending on the level of support from additional partners, it is anticipated that several multi-disciplinary teams (i.e., CIHR Team Grant Program) will be funded at a level up to $750,000/year for five years and "high risk" grants at a level up to $100,000/year for a maximum of two years.

Cardiovascular Complications of Diabetes - New Frontiers Program Workshop

In anticipation of an RFA launch in the area of cardiovascular complications of diabetes and to assist funding partners in crafting the most pertinent RFA, the CIHR Institute of Circulatory and Respiratory Health (ICRH) and the Heart and Stroke Foundation of Canada (HSFC) supported and participated in an international New Frontiers Program (NFP) workshop in May 2005. Other sponsoring partners included the:

The overarching objective of the NFP workshop was to discuss and identify knowledge gaps and research themes that could become the focus of an RFA, as well as possible funding mechanisms. The workshop, held May 28 to 29, 2005, in Toronto, Ontario, under the leadership of Drs. Peter Liu, Subrata Chakrabarti, Dan Drucker and George Fodor, was attended by over 60 invited, leading national and international researchers, and representatives from partner organizations and agencies.

In keeping with reporting requirements, the workshop leaders have submitted a synthesis report to ICRH and HSFC that summarizes the workshop discussions, knowledge gaps and recommendations of priority areas of potential research focus (click here for an electronic copy of the Executive Summary of the synthesis report). The following research themes were identified by workshop participants as possible foci for the planned RFA:

We hope you will review the workshop synthesis report and begin thinking about how you could respond to the upcoming planned RFA. Given that multi-disciplinary teams are a major focus of the upcoming RFA, interested researchers are encouraged to reflect upon the themes identified in the report and questions that are most likely to be answered by a team that draws on a breath of expertise, and to be ready to respond to the RFA when it is officially launched later this year. Applications that focus only on diabetes or cardiovascular disease will not be eligible for this RFA. Eligible applications must focus on the cardiovascular complications of diabetes.

Further details about this initiative will be available in early December 2005.

For more information about partnership opportunities and/or the initiative, please contact:

Ms. Salima Harji
Manager, Special Projects
CIHR Institute of Circulatory and Respiratory Health
Tel: 604-806-8658
Fax: 604-806-8935
E-mail: sharji@mrl.ubc.ca

Ms. Jennifer Gee Campbell
Assistant Director, Strategic Research Initiatives
Heart and Stroke Foundation of Canada
Tel: 613-569-4361, Ext. 350
Fax: 613-569-3278
E-mail: jgee@hsf.ca


Created: 2005-10-13
Modified: 2005-10-17
Reviewed: 2005-10-13
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