Index of Published Canadian Adverse Reaction Newsletters
October 2006; 16(4)
BioGlue: chronic inflammation and foreign-body reactions
New tool for reporting adverse reactions
Physician reporting of adverse reactions
Case presentation: Atomoxetine and tics
Summary of advisories
July 2006; 16(3)
Adverse reactions in children: Why report?
Case presentations:
Extended-release methylphenidate withdrawal: priapism
Iodoquinol: hypertensive encephalopathy and seizures
Symposium on drug, food and natural health product interactions
Summary of advisories
April 2006; 16(2)
Tenofovir and NSAIDs: acute renal failure
Adverse reaction reporting - 2005
Isotretinoin: myocardial infarction, cerebrovascular and thromboembolic disorders
Case presentation: Overnight orthokeratology and Acanthamoeba keratitis
Regional Adverse Reaction Centres: relocation
Summary of advisories
January 2006; 16(1)
Oseltamivir and warfarin: increase in INR
Levonorgestrel-releasing intrauterine system and uterine perforation
Guidance document for industry
Energy drinks
Case presentation: Rosiglitazone: parotid gland enlargement
Summary of advisories
October 2005; 15(4)
Intrathecal baclofen: pump system incidents
Statins and memory loss
Chloral hydrate and potassium chloride: medication incident
Case presentation: Ayurvedic medicines: lead contamination
New MedEffect e-notice and Web site
Summary of advisories
July 2005; 15(3)
Transdermal fentanyl: abuse in adolescents
Black cohosh: international reports of liver toxicity
Rosiglitazone: decreased HDL cholesterol levels
Ibuprofen: Stevens–Johnson syndrome
New Regional Adverse Reaction Centres
Case presentation: mefloquine with QT prolongation
Summary of advisories
April 2005; 15(2)
Hylan G-F 20 : joint inflammation and pain
Adverse reaction reporting - 2004
Products derived from bees: serious adverse reactions
Case presentation : rhabdomyolysis with clopidogrel, atorvastatin and cyclosporine
Summary of advisories
January 2005; 15(1)
Telithromycin and warfarin
Linezolid and neuropathy
Camphor and eucalyptus oils
Adverse reaction reporting
Natural weight loss product and myopathy
Ceftriaxone and immune hemolytic anemia in children
Case presentation :
olanzapine and pulmonary embolism
Summary of advisories
October 2004; 14(4)
Transdermal fentanyl (Duragesic): respiratory
arrest in adolescents
Infliximab (Remicade) and etanercept (Enbrel):
serious infections and tuberculosis
Bitter orange (synephrine): cardiovascular
reactions
Case presentations:
Ibutilide and torsades
de pointes
Tubersol and anaphylaxis
Summary of advisories
July 2004; 14(3)
Fluoroquinolones and warfarin: suspected interactions
Suspected warfarin-cranberry juice interaction
Case presentations:
- Tutoplast
Dura graft and Creutzfeldt-Jakob disease
- Toxic shock
syndrome and tampons
Summary of advisories
April 2004; 14(2)
Sterol and sterolin-containing products: hematologic
adverse reactions
Adverse reaction reporting - 2003
Feasibility study of active surveillance of
adverse reactions in children
Public opinion survey on post-market surveillance
Case presentation: clopidogrel
Summary of advisories
January 2004;
14(1)
Valdecoxib (BextraTM): severe cutaneous
reactions
Natural health products
Case presentations:
- Ciprofloxacin
- Finasteride
Drug Safety Information Workshop II Report
Human growth hormone (somatropin): Prader-Willi
syndrome
Summary of advisories
October 2003;
13(4)
Bisphosphonates and ocular disorders
Fluticasone and adrenal suppression
Adhesion prevention solutions in gynecological
procedures
Case presentation: intravenous immunoglobulins
Summary of Advisories
Insulin products
July 2003; 13(3)
Gatifloxacin (TequinTM ): hypoglycemia
and hyperglycemia
Serotonin syndrome
Summary of advisories
Case presentation: red yeast rice and rhabdomyolysis
April 2003; 13(2)
Withdrawal reactions with paroxetine
and other SSRIs
Adverse reaction reporting - 2002
Case presentation: divalproex
Safe use of products containing acetaminophen
Hormone replacement therapy
Summary of advisories
January 2003; 13 (1)
Suspected hepatobiliary reactions
to the newer antidepressants
Convulsions and newer-generation
antihistamines
Drug Safety Information Workshop Report
Case presentation: RespirActin
Summary of advisories
October 2002; 12 (4)
Natural Health Products: adverse reactions
Leflunomide (Arava): hematologic,
hepatic and respiratory reactions
Case Presentation: moxifloxacin
Summary of Advisories
Drugs and grapefruit: interactions
July 2002; 12 (3)
Pure red cell aplasia and
Eprex
Glitazones: update on adverse reactions
Safety of human insulins
Case presentation : Kava
Summary of Advisories
April 2002; 12 (2)
Marketed Health Products
Directorate
Selective COX-2 inhibitors
Summary of advisories
Oral sodium phosphates solutions
Case presentation
Adverse reaction reporting - 2001
January 2002; 12 (1)
Statins:
rhabdomyolysis and myopathy
Alendronate: suspected pancreatitis
HIV-associated
lipodystrophy syndrome: overview and summary of case reports
Summary of drug advisories
Communiqué - Ibuprofen pediatric
oral liquid: gastrointestinal bleeding
October 2001; 11(4)
Antitubercular
drugs: hepatobiliary reactions
Electronic subscription
to this Newsletter and drug advisories
Health professional
advisories
Atypical antipsychotics:
impaired glucose metabolism
Communiqué - Brimonidine (Alphagan)
ophthalmic drops: accidental ingestion
July 2001; 11(3)
Drug
advisories now available on the Web
Miconazole-warfarin interaction:
increased INR
New toll-free numbers
to report ADRs
Rosiglitazone (Avandia): hepatic,
cardiac and hematological reactions
Adverse
drug reaction reporting - 2000: Part 2
Communiqué
- Orlistat (Xenical) interaction with
coumarin derivatives: increased INR
- Azithromycin (Zithromax): myocardial
infarction
Drugs of Current Interest
April 2001; 11(2)
Adverse
drug reaction reporting - 2000: Part 1
Antiparkinsonian drugs
and "sleep attacks"
Rofecoxib (Vioxx): a year in review
Communiqué - Warfarin and glucosamine:
interaction
Drugs of Current Interest
January 2001; 11(1)
Thioridazine
(Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval
Clopidogrel (Plavix): hematological
reactions
Gentamicin ear drops and ototoxicity:
update
Drugs of Current Interest
October 2000; 10(4)
New
influenza drugs: unexpected serious reactions
Intravenous RhO
[D] immune globulin [human]: suspected hemolytic/renal adverse reactions
Abboject® Unit-of-Use Syringe: reports
of malfunction
Communiqué
- Glucosamine sulfate: hyperglycemia
- Ketotifen (Zaditen®): sleep
apnea
- Diclofenac
(Voltaren Ophtha®) and ketorolac
tromethamine
(Acular®): corneal ulceration
Drugs of Current Interest
July 2000; 10 (3)
St.
John's wort: harmful drug interaction
Olanzapine (Zyprexa): suspected
serious reactions
Sildenafil (Viagra): cardiac
risks
New Bureau Name
Communiqué
- Citalopram (Celexa) and
clarithromycin (Biaxin): interaction
- Itraconazole (Sporanox):
serum sickness-like disorder
Drugs of Current Interest
April 2000; 10 (2)
Adverse
drug reaction reporting - 1999
Celecoxib (Celebrex): 1 year later
Correction - ticlopidine
Communiqué - orlistat (Xenical):
pancreatitis
Drugs of Current Interest
January 2000; 10 (1)
Cisapride (Prepulsid):
interactions
Pemoline (Cylert): market withdrawal
Bupropion (Zyban): update
Communiqué
- HIV protease inhibitors: paronychia
- Gingko biloba: bleeding disorders
Drugs of Current Interest
October 1999;9(4)
Serious hematologic
reactions associated with ticlopidine - update
Leukotriene
receptor antagonists: suspected adverse reactions
Communiqué - Ropinirole (Requip):
sleep disorder
July 1999; 9(3)
Alteplase (Activase
rt-PA) for acute ischemic stroke
Abciximab (ReoPro): risk of acute thrombocytopenia
Nefazodone (Serzone) and hepatotoxicity
Communiqué - Amlodipine (Norvasc):
hearing loss
April 1999; 9(2)
Bupropion (Zyban):
suspected adverse reactions
1998 ADR Statistics
Updates: immune globulin IV products,
tolcapone (Tasmar)
Communiqué - Olanzapine (Zyprexa):
priapism
January 1999; 9(1)
Isotretinoin and
depression
Low-dose ASA and GI Bleeding
Guidelines for reporting ADRs
Communiqué - azithromycin, pentoxifylline,
sertraline and carbamazepine: interaction
October 1998; 8(4)
Recent News About Drug
Risks
New Ontario Regional
ADR Centre
Discontinuation Reactions Associated With
SSRIs
Communiqué - amantadine and warfarin,
pantoprazole
July 1998; 8(3)
Quality Information
in Spontaneous Reports
Donepezil: Suspected Adverse Reactions
Olanzapine: Hematological Reactions
Communiqué - valproic acid, cefaclor,
latanoprost, protease inhibitors
April 1998; 8(2)
Alendronate-induced
esophagitis
1997 ADR statistics
Communiqué - dorzolamide hydrochloride,
hydroxychloroquine sulfate, torvastatin calcium, risperidone, venlafaxine
hydrochloride
January 1998; 8(1)
Drugs:
QT interval prolongation and torsades de pointes
Ciprofloxacin use
in epileptic patients taking phenytoin
Appetite suppressants -
update
Communiqué - vigabatrin, mefloquine,
lamotrigine
October 1997; 7(4)
Calcium-channel
blockers
Azithromycin - severe iatrogenic
hepatitis
Newsletter survey results
Communiqué - protease inhibitors,
vigabatrin, terconazole, Fen-phen, heparin, paroxetine
July 1997; 7(3)
ACE inhibitors
and bronchospasm
Interferon beta-1b
Radiopharmaceuticals
New Expert Advisory Committee
on Pharmacovigilance
April 1997; 7(2)
Adverse
drug reaction reporting - 1996
Potential abuse of butorphanol
nasal spray
Aminoglycoside ear drops and ototoxicity
January 1997; 7(1)
Primary
pulmonary hypertension and appetite suppressants
HIV protease inhibitors
and increased bleeding in hemophilia?
Erythema multiforme and nifedipine
Congenital anomalies and
fluconazole
October 1996; 6(4)
Cefaclor-associated serum
sickness-like reaction
Newsletter Assessment - Questionnaire
July 1996; 6(3)
Cisapride: Arrhythmia Awareness
Midazolam: A Wake-Up Call
Clarithromycin: Tooth Discolouration and Smell Alteration
April 1996; 6(2)
Metformin: Lactic Acidosis
Nefazodone: ADR Profile
1995 Statistics ADR or Product Fault?
January 1996; 6(1)
Cotrimoxazole
Nicotine Patches and exercise
Terbinafine - hepatobiliary reactions
SSRIs - hyponatremia
October 1995; 5(4)
Update: Fertility Drugs
Propofol: Convulsions
Contraindications: Dinoprostone
Vaginal Gel
DOCI List
July 1995; 5(3)
Reporting Adverse Drug Reactions
Lamotrigine (Lamictal): rashes
Drug Names: confusion from two fronts
Tiaprofenic Acid: cystitis
Ticlopidine: revisited
DOCI List
April 1995; 5(2)
Zidovudine: Benefits of use during pregnancy
Serevent®: Patient warnings must be stressed
Fluoroquinolones: Tendonitis
Topical Antifungals: Recent switch to over-the-counter
Phenazopyridine: Hemolytic anemia
January 1995; 5(1)
Risperidone and EPS Sumatriptan and migraine exacerbation
Bromocriptine
Fertility drug awareness
New regional centre for Quebec
October 1994; 4(3)
Regional Centres
New Drugs - Serzone, Neurontin, Sabril
Drugs of current interest
July 1994; 4(2)
Editorial Note
Terbinafine Herbal preparations
March 1994; 4(1) Rhabdomyolysis and HMG-CoA
Reductase Inhibitors
Antidepressants and Suicide
Help Wanted: Risperdal
November 1993; 3(2)
Ticlopidine HCl - Hematological and Liver Effects
H1-Antihistamines - Cardiotoxic Effects
August 1993; 3(1)
ACE Inhibitors: Renal Effects
Sumatriptan Succinate: Chest Pain
Nicotine Patches: Update / Inadvertent Exposure
April 1992; 2(1)
ADR Program, 1991 Annual Report
Case Report: Drug Interactions with Omeprazole
Vasospasm with B-Blockers
GI Bleeding with Toradol®
August 1991; 1(2)
PPSP Workshop Minocycline - Case reports of severe liver and renal reactions
ADRs in the Elderly Ciprofloxacin - ADR profile Diclofenac - Hepatic reactions
January 1991; 1(1)
Saskatchewan ADR Pilot Project
The WHO Connection Working Group on ADR Assessment
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