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Institute of Circulatory and Respiratory Health (ICRH)

Enhancing Canada-United States Collaboration in Circulatory and Respiratory Health Research: Special Requests for Applications

Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine

The CIHR Institute of Circulatory and Respiratory Health (ICRH) and the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) have agreed to collaborate on a fourth research area: cardiac surgery.  This joint initiative is intended to enhance collaboration between Canadian and United States researchers and build synergy between the two countries.

Note: We would appreciate knowing if Canadian applicants plan to submit an application to this funding opportunity and ask that you inform us of your intent to apply by sending a brief email to Katherine Gardner (kgardner@cihr-irsc.gc.ca). Formal letters of intent and full applications should be sent to NHLBI, as indicated in the RFA.

Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine

The National Institutes of Health and the Canadian Institutes of Health Research invite applications to participate in the Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine (Network), a cooperative network of academic centers with clinically active cardiothoracic surgeons and their colleagues in allied specialties interested in promulgating the use of evidence-based medicine in surgical practice. The goal of the Network is to foster a culture of rigorous scientific comparisons and promote the evaluation of newer surgical techniques, technologies, devices, and innovative pharmaceutical and bioengineered products directed at cardiovascular disease.  The Network will allow research teams led by cardiac surgeons to evaluate, by the most rigorous methods possible, newer therapies and techniques as they move from laboratory science to broad clinical use.  The Network will enhance the capacity to disseminate study results, and translate findings to large-scale trials or practice. The program will provide support to maintain the necessary infrastructure to develop, coordinate, and conduct multiple collaborative proof-of-concept clinical studies and interventional protocols to improve cardiovascular disease outcomes.

Up to seven awards will be made for Clinical Centers and one award for a Data Coordinating Center. Approximately $35 million (total costs) over 5 years will be awarded with $5M the first year. It is anticipated that the annual award for the Data Coordinating Center will be approximately $1.1M direct costs in the first year and $1.4M each year for years two through five. The maximum annual amount for each Clinical Center will be $250,000 direct costs.  An additional budget of $13.2M for protocols and related patient costs for the entire five-year study period is anticipated. A maximum of two Clinical Skills Development Core awards will be made for up to $100,000 per year (direct costs).

Release Date: March 3, 2006
Letters of Intent Receipt Date(s): July 28, 2006
Application Receipt Dates(s): August 28, 2006
Peer Review Date(s): February/March 2007
Council Review Date(s): June 2007
Earliest Anticipated Start Date: July 1, 2007
Additional Information: Frequently Asked Questions for RFA-HL-06-005
Expiration Date: August, 29, 2006

Scientific/Research Contact at NHLBI:

Marissa A. Miller D.V.M., M.P.H.
Division of Heart and Vascular Diseases
National Heart, Lung, and Blood Institute
6701 Rockledge Dr.
Rockledge II, 9180
Bethesda, MD 20892
Telephone: (301) 594-1542
FAX: (301) 480-1336
Email: Millerma2@mail.nih.gov

Created: 2006-05-03
Modified: 2006-05-03
Reviewed: 2006-05-03
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