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André Cantin, MD, LMCC, CSPQ, FRCPC (Chair)
Professor
Department of Medicine, Respiratory Division
University of Sherbrooke
Dr. André Cantin obtained his MD degree at the University of Sherbrooke in 1978, and subsequently trained in Internal Medicine and Respiratory Medicine at the same institution from 1979 - 1982. He became a fellow of the Royal College of Physicians of Canada with certification in Pulmonary Medicine in 1983. He completed a fellowship at the National Institutes of Health in the Pulmonary Division under the supervision of Dr. Ronald G. Crystal from 1982 - 1985. He has been a member of the Pulmonary Division at the University of Sherbrooke since 1985 and is currently a professor in the Department of Medicine. His research interests are in the areas of lung inflammation, oxidants and antioxidants in pulmonary fibrosis and cystic fibrosis. He is currently the chair of the Medical and Scientific Advisory Board of the Canadian Cystic Fibrosis Foundation and was the chair of the Respiratory System grants committee at the Medical Research Council of Canada from 1998 - 2000. He is also the director of the Special Programme in Applied Research and Therapeutics (SPARX1) of the CCFF, a programme designed to accelerate the development of novel therapies for lung disease in patients with cystic fibrosis.
Paul W. Armstrong, MD
Professor of Medicine
University of Alberta
Dr. Paul Armstrong is Professor of Medicine in the Division of Cardiology at the University of Alberta, Edmonton, Alberta, Canada and Director of the Canadian VIGOUR Centre. He is Director of the CIHR program training grant TORCH (Tomorrow's Research Cardiovascular Health Professionals) that represents a synergistic partnership between the universities of Alberta and Calgary. He is a Senior Attending Cardiologist at the University of Alberta Hospital with particular interest and expertise in acute coronary care and heart failure. In the latter capacity he serves as Director of the University of Alberta Hospital Heart Function Clinic. Dr. Armstrong received his medical degree at Queen's University, Kingston, Ontario, Canada and after post-graduate training both there and at the University of Toronto, Ontario, Canada he undertook clinical and research training in cardiology at the Massachusetts General Hospital, Harvard Medical School, MA, USA and St. George's Hospital, London, UK.
Dr. Armstrong's investigative career has developed along two major lines of inquiry. The first involved the study of the pathophysiology and novel therapeutic approaches of congestive heart failure using an experimental model as well as undertaking clinical investigative studies. The second, which is now his principal focus, involves the pathophysiology, diagnosis and management of acute coronary syndromes. He has a particular interest in the analysis of international differences in the process of cardiovascular care and their implications for the Canadian health care system.
Dr. Armstrong is the author, or co-author of over 300 peer reviewed publications and a member of the editorial board of a number of publications, including the Canadian Medical Association Journal, Canadian Journal of Cardiology, the American Heart Journal and Circulation Section Editor of New Frontiers. He also serves as a member on the FDA Cardiovascular and Renal Drugs Advisory Committee. In 1993, Dr. Armstrong received the Research Achievement Award from the Canadian Cardiovascular Society, and in 1998, the Award of Merit from the Heart and Stroke Foundation of Canada for contributions to medical research.
Jacques de Champlain, OC, OQ, MD, PhD, FRSC, FAHA, FIACS, FCAHS, FRCPC
Professeur titulaire
Département de physiologie et médecine
Université de Montréal
Jacques de Champlain is Research Professor in the departments of Physiology and Medicine of the Faculty of Medicine at the Université de Montréal. He is the Director of the Research Group on Autonomic Nervous System (GRSNA) since 1987. Doctor de Champlain is also a researcher at the Montreal Clinical Research Institute, where he is Director of the Clinical Research Unit on the Autonomic Nervous System.
Doctor de Champlain earned a medical degree from the Faculty of Medicine at the University of Montreal and a PhD degree from McGill University (Department of Investigative Medicine). He subsequently completed his postgraduate training at the NIH in Bethesda (USA) with Dr Julius Axelrod (Nobel Prize laurate 1971) and at the Karolinska Institute in Stockholm, Sweden.
During his career, he has made several contributions to the understanding of the role of the renin-angiotensin and autonomic nervous system as well as on the role of oxidative stress in experimental models of hypertension and diabetes and in human hypertension. He is the author or coauthor of more than 300 peer reviewed papers and book chapters.
Doctor de Champlain was founding member and President of the Canadian and the Quebec Hypertension Societies, as well as Council Member of the International Society of Hypertension and he has also been recognized as "Hypertension Specialist" by the American Society of Hypertension.
Doctor de Champlain has been awarded several prizes, including the Izaak-Walton-Killam Award from the Canada Council for the Arts, the Wilder-Penfield Award from the Government of Quebec, the McLaughlin medal from the Royal Society of Canada, the Merck, Sharp and Dohme international Award from the International Society of Hypertension as well as Career Achievement Awards from the Canadian Hypertension Society, the Canadian Cardiovascular Society, l'Association de Médecins de Langue Française and from Le Club de Recherches Cliniques du Québec. He has also received many honors including his appointments as Officer of both the Order of Canada and the National Order of Quebec as well as his election as a member of the Canadian Academy of Sciences and of the Canadian Academy of Health Sciences.
Dana Devine, PhD
Director of Research and Development, Canadian Blood Services
Professor, Department of Pathology and Laboratory Medicine
University of British Columbia
Dr. Dana V. Devine received her PhD in Immunology from Duke University, North Carolina, 1986. In 1987, she joined the Canadian Red Cross Society Blood Services as a scientist and accepted her first faculty position with the University of British Columbia where she is currently a Professor of Pathology and Laboratory Medicine and an Associate Member of the Department of Biochemistry and Molecular Biology. She is also a faculty associate of the Peter Wall Institute for Advanced Studies at UBC. In 1999 she was appointed national Director of Research & Development for Canadian Blood Services. Her central focus of research for the past decade has been platelet biology, complement biochemistry, blood coagulation and transfusion medicine. This research has been funded by the MRC/CIHR, the Heart and Stroke Foundation and Canadian Blood Services. She has published over 80 peer-reviewed publications, book chapters and invited reviews. Dr. Devine is a former Vice-President of the Heart and Stroke Foundation of BC and Yukon.
Gregory Downey, MD, FRCPC, FCCP
Professor of Medicine
University of Toronto
Dr. Gregory Downey currently holds research funding from the Canadian Institutes of Health Research, Canadian Cystic Fibrosis Foundation, and National Institutes of Health (USA). His research program has focused on cell signaling in regulation of leukocyte function as it pertains to lung inflammation in sepsis and acute lung injury and pulmonary host defense. One major theme of his research program pertains to the importance of the cytoskeleton in the regulation of cellular biophysical properties and transmembrane and intracellular signaling pathways. A second major area has been the delineation of the importance of intracellular signaling pathways in regulation of leukocyte activation. Included in this area are his studies investigating the regulation of adhesion, oxidant production, and phagocytosis. A closely related area pertains to the role of tyrosine phosphatases such as CD45 and SHP-1 in regulation of leukocyte activation.
Peter Glynn, PhD
Health Care Consultant
Adjunct Professor, Community Health and Epidemiology,
Queen's University
Chairman of the Board, Institute for Clinical Evaluative Sciences in Ontario
Dr. Glynn is a consultant on health care policy, planning, governance and management, both in Canada and internationally. In June 2000, after ten years service, he retired from the position of President and Chief Executive Officer of the Kingston General Hospital, a 450-bed teaching hospital affiliated with Queen's University. During that period, he led the hospital through an unprecedented period of reform and financial constraint. Formerly, he was the Assistant Deputy Minister, Health Services and Promotion Branch, Health and Welfare Canada and, prior to that, the Associate Deputy Minister of Health for the Province of Saskatchewan.
He has been a member of, and chaired, many task forces, committees and organizations in health care and health research. He was a member of both the CIHR Task Force and the Interim Governing Council. He has been a member of the Board of the Heart and Stroke Foundation of Canada and the National Cancer Institute of Canada. He is the Chair of the Board of the Institute of Clinical Evaluative Sciences and the Chair of the Governing Council of the Centre for Studies in Primary Care at Queen's University. He is also the Chair of the Saskatchewan Surgical Care Network.
Dr. Glynn is an Associate Professor (Adjunct) in the Department of Community Health and Epidemiology at Queen's University. He has received recognition from many health organizations and universities for leadership and innovative thinking. Dr. Glynn holds a Bachelor of Engineering from the Royal Military College of Canada and a PhD in Engineering from the University of Waterloo.
Pavel Hamet, MD, PhD, CSPQ, FRCP
Directeur de la recherche
Centre Hospitalier
Université de Montréal (CHUM)
A Canadian citizen, born in the Czech Republic, Dr. Pavel Hamet completed his medical studies at Charles University, Prague. After being awarded a Centennial Fellow from the Medical Research Council in 1973, he studied endocrinology and physiology at Vanderbilt University, Nashville, Tennessee, from July 1973 to June 1975. He is Director of Research, Research Centre of the Centre hospitalier de l'Université de Montréal, and Professor at the Departments of Medicine, Physiology and Nutrition at the University of Montreal and Adjunct Professor at the Department of Medicine at McGill University. Dr. Hamet is the author and co-author of over 350 manuscripts, published in well-recognized peer-reviewed journals and books of scientific interest.
Dr. Hamet receives financial support from major funding institutions, such the Medical Research Council of Canada and the National Institutes of Health (USA) as well as from the pharmaceutical industry. He was President of the Canadian Hypertension Society and Secretary of the International Society of Hypertension. He received many prizes, including the "Harry Goldblatt Award" from the American Heart Association in 1990 for his achievements in the field of hypertension. In 1994, he was appointed Honorary Professor of the Shanghai II Medical University, Shanghai, China and he received the Golden Medal of J.E. Purkyne of the Czech Academy of Sciences, Prague, Czech Republic the same year. In 1996, Dr. Hamet received the Distinguished Scientist Award of The Canadian Society for Clinical and the Achievement Award of the Canadian Cardiovascular Society in 1998.
Dr. Hamet serves on many national and international boards including Medical Research Council of Canada/Rx&D, Institut national de la recherche scientifique (INRS), Centre d'entreprises et d'innovation de Montréal, BioCapital Inc., PharmaVision Inc., Montreal TechnoVision Inc., Vasogen Inc., ConjuChem Inc., Angiogene Inc.
Tara Haas, PhD
Associate Professor
School of Kinesiology and Health Sciences
York University
Dr. Tara Haas is currently an associate professor in the School of Kinesiology and Health Sciences at York University.
She completed her bachelor's degree in human kinetics at the University of Guelph (1990), her PhD in physiology at the University of Virginia (1995) and received postdoctoral training at Yale University (1999) prior to taking a faculty position at York. Dr. Haas's research program focuses on the process of angiogenesis, new capillary growth within skeletal and cardiac muscle, and understanding how this process may be stimulated by exercise. A major component of this research involves mapping the intracellular signaling and transcriptional regulation of matrix metalloproteinases within endothelial cells, as these enzymes play a critical role in early phases of angiogenesis.
Dr. Haas currently holds a CIHR New Investigator Award, Premiers Research Excellence Award, and funding from the Natural Sciences and Engineering Research Council (NSERC) and the National Institutes of Health (NIH). She is a council member for the Microcirculatory Society.
Kathryn King, PhD
Associate Professor and Heritage Population Health Investigator
Faculty of Nursing
University of Calgary
Dr. Kathryn King is an Associate Professor and Heritage Population Health Investigator in the Faculty of Nursing and Department of Community Health Sciences at the University of Calgary. She earned a BSc in Nursing from McMaster University in 1980 and a Masters and PhD in Nursing from the University of Alberta in 1993 and 1997 respectively. She undertook post-doctoral training in the Faculty of Medicine, Division of Cardiology (EPICORE Centre) between 1997 and 1999 and was appointed to the University of Calgary in 1999. Her multi-methods program of research, funded by AHFMR, SSHRC and CIHR, focuses on recovery from cardiac events. In particular she has examined the influences of gender/sex and ethnocultural affiliation on various components of cardiac recovery. Dr. King served as the national research chairperson for the Canadian Council of Cardiovascular nurses between 1998 and 2003.
Andreas Laupacis, MD, MSc, FRCPC
President and CEO
Institute for Clinical Evaluative Sciences
Professor, Faculty of Medicine
University of Toronto
With over 200 articles published in peer reviewed journals, Dr. Laupacis is a general internist, President and Chief Executive Officer of the Institute for Clinical Evaluative Sciences (ICES), and a professor in the Departments of Medicine and Health Policy Management and Evaluation at the University of Toronto.
He received his master of science degree with a concentration in Design, Measurement and Evaluation, at McMaster University in 1986, and his medical degree from Queen's University in 1979.
Dr. Laupacis' initial research interests were in the design and execution of multi-centre clinical trials, evaluating methods of presenting the results of clinical trials to patients and clinicians, and health care technology assessment. Contributions that he has made to the literature include a) articulation of the number needed to treat (with David Sackett), b) studies of anti-thrombotic therapy to prevent stroke in patients with atrial fibrillation (with numerous collaborators), c) evaluation of the role of erythropoietin in patients with end stage renal failure (with Paul Keown and others), and d) the development of decision aids for patients and physicians (with Annette O'Connor and colleagues at Ottawa). More recently, Dr. Laupacis has become involved in the areas of pharmacoeconomics, drug policy and the use of diagnostic tests.
He is currently Chair of the Canadian Expert Drug Advisory Committee (CEDAC) and is a member of Health Canada's Science Advisory Board.
Peter Liu, MD
Director, Heart & Stroke, Richard Lewar Centre of Excellence
Heart & Stroke/Polo Chair Professor of Medicine and Physiology
University of Toronto
Dr. Peter Liu's current appointments include the Heart and Stroke/Polo Chair Professor of Medicine and Physiology, University Health Network, Director, Heart & Stroke/Richard Lewar Centre of Excellence in Cardiovascular Research, University of Toronto, and Associate Director, Division of Cardiology, University of Toronto. He is also the current Director of the CIHR Group Program in Heart Failure (CHF-CORE), the CIHR Canadian Heart Failure Interdisciplinary Health Research Network (CHFNET), the CIHR Strategic Program in Training for Cardiovascular Excellence (TACTICS), and is current Chair of the Scientific Program Committee, Heart Failure Society of America.
Dr. Liu received an MD from the University of Toronto in 1978. He completed his postgraduate training in Internal Medicine and Cardiology at University of Toronto, Cardiovascular Training & Research at Harvard Medical School, Boston, and Clinical Epidemiology at McMaster University. Dr. Liu's recent honours include the A.L. Burton Lecturer from the University of Western Ontario in 2002, the John Foerster Research Award, University of Manitoba in 2003, the Rick Gallop Research Excellence Award, Heart & Stroke Foundation of Ontario/Canada in 2003, and Research Achievement Award, Canadian Cardiovascular Society in 2003.
Dr. Liu is the author or coauthor of over 200 peer review publications, including Nature, Nature Medicine, New England Journal of Medicine, Journal of Clinical Investigation, Circulation, Circulation Research, etc., and 20 book chapters. His areas of research interest include Inflammatory and immune mechanisms of cardiovascular disease; role of host responses to cardiovascular injury in producing heart failure, investigated through the use of transgenic mouse models; and translation of heart failure investigation from the bench to the bedside through clinical trials & health service research.
Jean Marion, PhD
Director, Scientific Affairs
Rx&D
Jean Marion is currently Director, Scientific Affairs at Canada's Research-Based Pharmaceutical Companies (Rx&D) as well as Executive Director of Rx&D's Health Research Foundation. From 1999 to 2001, Jean was seconded to Canada Revenue Agency (CRA). As a National Technology Sector Specialist within CRA's Scientific Research and Experimental Development Program, he played a key role in developing application policies for the pharmaceutical and biopharmaceutical sector. Jean originally joined Rx&D from Merck Frosst Canada where he managed clinical studies as a Clinical Research Project Manager. Prior to joining the private sector, Jean was part of a team at Industry Canada working to improve the business environment affecting the pharmaceutical industry. His career in government also included a posting to the Canadian Embassy in Brussels as a Science and Technology Counsellor and a role in the implementation of the University-Industry Program at the Natural Sciences and Engineering Research Council (NSERC). Jean received a doctorate degree in biochemistry from McGill University in 1980 and held an Industrial Research Fellowship at Ayerst Laboratories and Bioresearch Laboratories.
Graham Nichol, MD
Associate Professor of Medicine, University of Ottawa
Senior Scientist, Clinical Epidemiology
Ottawa Health Research Institute
Dr. Graham Nichol is an Associate Professor of Medicine, Epidemiology and Community Medicine, at University of Ottawa. He completed his Doctor of Medicine in 1988 and internal medicine training at the University of Western Ontario. During this time, he developed an interest in learning how to choose which health interventions should be used to improve care. Then he completed a fellowship focused on an evaluation of the effectiveness and costs of use of treatments for patients with sudden cardiac arrest. He subsequently completed a two-year fellowship in clinical epidemiology at Brigham and Women's Hospital and Harvard School of Public Health (MPH 95).
The aim of Dr. Nichol's research is to develop, implement, evaluate and disseminate effective and inexpensive interventions for cardiovascular disease including drugs and devices; social, educational or economic interventions; and simple interventions available at onset of acute cardiovascular event. Dr. Nichol has focused his career on applied and methodological research related to the evaluation of the effectiveness and efficiency of cardiovascular interventions because cardiovascular disease is common, lethal, debilitating and costly.
Since he volunteered in New York City on September 11, 2001, his mission has become to improve outcomes after resuscitation from sudden cardiac arrest or traumatic injury.
Benjamin Rusak, PhD
Professor, Departments of Psychiatry and Psychology and Director, Research Section
Dalhousie University
Director, Chronobiology and Sleep Program
Queen Elizabeth II Health Sciences Centre
Dr. Rusak graduated from the University of Toronto and received a PhD from the University of California, Berkeley. He is currently a University Research Professor in the Departments of Psychiatry, Psychology and Pharmacology at Dalhousie University. He has served as the Director of Research in Psychiatry since 2000, and in 2003-04 was an Acting Assistant Dean (Research) in the Faculty of Medicine. Dr. Rusak's primary research interests are in the basic mechanisms regulating circadian (daily) rhythms and sleep in mammals, and in applying knowledge of these mechanisms to issues in human health. His current research includes both individual and collaborative projects in the following areas: molecular, neurophysiological and behavioural approaches to circadian and sleep mechanisms; functional brain imaging studies of the effects of sleep deprivation in depression; studies of animal models of depression; and the effects of disrupted sleep on human performance; and on pain syndromes in children. The research contributions of his laboratory have been recognized by his election as a Fellow of the Academy of Sciences of the Royal Society of Canada (1999), his appointment as a Dalhousie Faculty of Science Killam Professor (1995-2000), and as a University Research Professor (2002-07).
Dr. Rusak was the founding Editor of the Journal of Biological Rhythms (1986-94) and has served on the editorial boards of Neuroscience & Biobehavioral Reviews and Sleep, on the Board of Directors of the Canadian Association for Neuroscience, on the International Selection Committee for the Honma Prize for Circadian Rhythmicity, on the Executive of the Society for Research on Biological Rhythms, and as a member of grant review panels for MRC/CIHR, NSERC, NSHRF and NIH (USA). He is currently the Vice-President, Research for the Canadian Sleep Society, a Canadian delegate to the World Federation of Sleep Research Societies, and served as the CIHR University Delegate to Dalhousie (2001-2004).
Dr. Rusak hopes to promote awareness of the significance of circadian rhythmicity and sleep to human health, and of the contributions of circadian factors and sleep disorders to cardiovascular and respiratory disease.
Brian Rutt, PhD
Scientist, Imaging Research Laboratories
Robarts Research Institute
Professor, Diagnostic Radiology and Nuclear Medicine
University of Western Ontario
Dr. Brian Rutt is currently a Scientist at the Robarts Research Institute and a Professor at the University of Western Ontario in London, Ontario, where he has been since 1986. Dr. Rutt received graduate degrees from Stanford University and the University of Toronto. He pursued postdoctoral work at the University of California, San Francisco.
Dr. Rutt's research is focused on quantitative measurement of anatomical and functional characteristics of the vasculature using magnetic resonance imaging (MRI). He leads several ongoing projects involving the development of improved methods for acquiring and displaying MR angiograms i.e. images of blood vessels, and assessing atherosclerotic plaque composition, morphology and vulnerability by MRI. He also works on the development of high-speed MRI techniques that will allow the acquisition of complete image sets in seconds rather than minutes. This research is aimed at solving the very real problem of low patient throughput in clinical MRI departments, and in addition is aimed at the development of dynamic scanning methods. Dr. Rutt is also working in the area of MRI hardware development and specifically the development of advanced "receiver coils", which receive the very weak magnetic signals that emanate from the patient's body, and advanced "gradient coils" which produce the spatial resolution in MR images. These coil developments are aimed at improving image quality by customizing coils to patient anatomy.
Sylvie Stachenko, MD, MSc, FCFP
Deputy Chief Public Health Officer
Public Health Agency of Canada
Dr. Sylvie Stachenko is currently the Deputy Chief Public Health Officer at the Public Health Agency of Canada.
Dr. Stachenko earned a bachelor of science degree from France's Université de Caen (1968), a bachelor of science degree in biophysics (1971) and a doctorate in medicine (1975), both from McGill University, and completed her residency in family medicine at the Université de Montréal (1977). She earned a master`s degree in epidemiology and health services administration from the Harvard School of Public Health in 1985.
Dr. Stachenko was an associate professor in the Department of Family Medicine at the Université de Montréal, where she served as Research Director from 1984 to 1988. In 1988, she joined the federal government with the Department of Health and Welfare and, in 1989, was appointed Director, Preventive Health Services.
From 1997 to 2002, Dr. Stachenko worked with the World Health Organization (WHO) Regional Office for Europe, located in Copenhagen, Denmark, as their Director of Health Policy and Services. She was then appointed Director General in the Centre for Chronic Disease Prevention and Control at the Public Health Agency of Canada, a position she held until 2004.
Lori West, MD, PhD
Professor of Pediatrics and Surgery
Director of Heart Transplantation Research
Department of Pediatrics
University of Alberta
Dr. Lori West is the Director of Heart Transplantation Research and a Professor of Pediatrics and Surgery at the University of Alberta Stollery Children's Hospital - one of the largest heart transplant programs in the world.
Dr. West completed her paediatric residency at Harbor-UCLA Medical Center and came to the Hospital for Sick Children, Toronto in 1987 to complete a two-year clinical fellowship in paediatric cardiology. She obtained her PhD for specialized training in transplant immunology research at Oxford University.
Dr. West's research focuses on overcoming the body's immune system response to foreign tissue. She discovered that infant heart transplants can be performed safely and successfully despite major blood type incompatibility between the donor and recipient.
Dr. West has over 58 peer-reviewed publications, has contributed to policy and has been invited to make over 95 presentations at conferences around the world. She has been interviewed on national TV, radio and featured in newspapers across North America.
