Arsenic and its Compounds - PSL1

Environment Canada
Health Canada
1993
ISBN: 0-662-20488-3
Cat. No.: En40-215/14E

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(753K)

Canadian Environmental Protection Act

Table of Contents

• Synopsis
• 1.0 Introduction
• 2.0 Summary of Information Critical to Assessment of "Toxic"
  • 2.1 Identity, Properties, Production and Uses
  • 2.2 Entry into the Environment
  • 2.3 Exposure-related Information
    • 2.3.1 Fate
    • 2.3.2 Concentrations
  • 2.4 Effects-related Information
    • 2.4.1 Essentiality and Toxicokinetics
    • 2.4.2 Experimental Animals and In Vitro
    • 2.4.3 Humans
    • 2.4.4 Ecotoxicology
• 3.0 Assessment of "Toxic" under CEPA
  • 3.1 CEPA 11(a): Environment
  • 3.2 CEPA 11(b): Environment on Which Human Life Depends
  • 3.3 CEPA 11(c): Human Life or Health
    • 3.3.1 Population Exposure
    • 3.3.2 Effects
  • 3.4 Conclusions
• 4.0 Recommendations for Research and Evaluation
• 5.0 References

List of Tables

• Table 1 Epidemiological Studies of Occupationally Exposed Populations (Modified from U.S. Environmental Protection Agency, 1984; Additional Recent Studies Have Also Been Included)
• Table 2 Estimated Total Daily Intake of Inorganic Arsenic for a 1 Kg Adult Mink Living along Mitchell Brook, Near an Abandoned Gold Mine at Waverley, Nova Scotia
• Table 3 Estimated Average Daily Intake of Inorganic Arsenic by Canadians
• Table 4 Estimated Daily Intake of Inorganic Arsenic by Canadians Living Near Point Sources

List of Figures

• Figure 1 Arsenic Concentrations in Canadian Surface Waters and Biological Effects at Corresponding Levels of Exposure
• Figure 2 Arsenic Concentrations in Canadian Sediments and Biological Effects at Corresponding Levels of Exposure
• Figure 3 Arsenic Concentrations in Canadian Soils and Biological Effects at Corresponding Levels of Exposure
• Figure 4 Exposure-response Relationship for Inhaled Arsenic and Respiratory Cancer in Smelter Workers

Notice to Readers

Pesticidal uses of arsenic were not assessed in this report. The pesticide arsenic pentoxide is subject to the provisions of the Pest Control Products Act, and its regulatory status as a heavy duty wood preservative is currently being re-evaluated (see Announcement A92-02: Re-evaluation of Heavy Duty Wood Preservatives, Agriculture Canada, Food Production and Inspection Branch, July 2, 1992). As part of the pesticide re-evaluation process, Environment Canada and Health Canada will assess the potential effects on the environment and on human health resulting from these pesticidal uses of arsenic.