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MATERIAL SAFETY DATA SHEET - INFECTIOUS SUBSTANCES SECTION I - INFECTIOUS AGENT NAME: Streptococcus salivarius SYNONYM OR CROSS REFERENCE: Viridans streptococci CHARACTERISTICS: Gram-positive cocci ~ 2 µm occuring in pairs and short chains; facultative anaerobe; non- or alpha hemolytic on blood agar SECTION II - HEALTH HAZARD PATHOGENICITY: Organisms colonize upper respiratory tract within first few hours after birth and are normal inhabitant of oral cavity, oropharynx and upper respiratory tract; infrequently pathogenic; Viridans streptococci species cause most dental caries and are the most frequent cause of subacute native valve bacterial endocarditis, typically associated with dental procedures; S. salivarius may cause septicemia in neutropenic patients EPIDEMIOLOGY: World wide; Dental caries common; persons with previously damaged heart valves are susceptible HOST RANGE: Humans INFECTIOUS DOSE: Not known MODE OF TRANSMISSION: Normal inhabitant of upper respiratory tract - trauma (dental work, brushing teeth, etc.) results in organisms entering into the blood stream INCUBATION PERIOD: Not known COMMUNICABILITY: Not transferred from person-to-person SECTION III - DISSEMINATION RESERVOIR: Humans ZOONOSIS: None VECTORS: None SECTION IV - VIABILITY DRUG SUSCEPTIBILITY: Sensitive to penicillin and erythromycin SUSCEPTIBILITY TO DISINFECTANTS: Susceptible to many disinfectants - 1% sodium hypochlorite and 70% ethanol, formaldehyde, glutaraldehyde, iodines PHYSICAL INACTIVATION: Sensitive to moist heat (121° C for at least 15 min) and dry heat (160-170° C for at least 1 hour) SURVIVAL OUTSIDE HOST: Rim of drinking glass - at least 2 days; the organism has been isolated from the intestinal contents of houseflies SECTION V - MEDICAL SURVEILLANCE: Monitor for symptoms of infection; confirm bacteriologically and immunologically in acute stages FIRST AID/TREATMENT: Antibiotic therapy with penicillin (erythromycin for those sensitive to penicillin) IMMUNIZATION: None available PROPHYLAXIS: Monthly administration of benzathine penicillin or daily use of oral penicillin for those at greatest risk of infection SECTION VI - LABORATORY HAZARDS LABORATORY-ACQUIRED INFECTIONS: 78 recorded cases of Streptococcus spp. with 4 deaths up to 1976 SOURCES/SPECIMENS: Blood, throat cultures, sputum, respiratory secretions PRIMARY HAZARDS: Accidental parenteral inoculation SPECIAL HAZARDS: None SECTION VII - RECOMMENDED PRECAUTIONS CONTAINMENT REQUIREMENTS: Biosafety level 2 practices, containment equipment and facilities for all activities involving known or potentially infected clinical materials or culture PROTECTIVE CLOTHING: Laboratory coat; gloves when contact with infectious materials in unavoidable OTHER PRECAUTIONS: None SECTION VIII - HANDLING INFORMATION SPILLS: Allow aerosols to settle; wearing protective clothing, gently cover spill with absorbent paper towel and apply 1% sodium hypochlorite, starting at perimeter and working towards the centre; allow sufficient contact time (30 min) before clean up DISPOSAL: Decontaminate before disposal; steam sterilization, chemical disinfection, incineration STORAGE: In sealed containers that are appropriately labelled SECTION IX - MISCELLANEOUS INFORMATION Date prepared: April, 2001 Prepared by: Office of Laboratory Security, PHAC Although the information, opinions and recommendations contained in this Material Safety Data Sheet are compiled from sources believed to be reliable, we accept no responsibility for the accuracy, sufficiency, or reliability or for any loss or injury resulting from the use of the information. Newly discovered hazards are frequent and this information may not be completely up to date. Copyright © [Material Safety Data Sheets - Index]
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Last Updated: 2001-05-14 | ![]() |