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Home : Infectious Diseases : Avian Influenza : Human Health Issues related to Avian Influenza in Canada : Appendix A |
Human Health Issues related to Avian Influenza in Canada[Previous] [Table of Contents] [Next] Appendix A: Sample Avian Influenza (H7N3) Outbreak Case Definitions for Investigation of Human Cases Associated with Domestic Avian Influenza Outbreaks[based on BC Avian Influenza (H7N3) Outbreak Case Definitions, 2004] The following definitions were developed by the national Respiratory Infections Surveillance Committee (RISC) and the BC Centre for Disease Control to assist with the identification of human influenza A (H7) cases and infections associated with the avian influenza A (H7N3) poultry outbreak in Fraser Valley, British Columbia, which began in February 2004. It is expected that these definitions, which were last updated April 22, 2004, will be modified relative to specific information is obtained specific to the virus strain and the epidemiology and clinical presentation of cases. These sample case definitions are intended to serve as a starting point for jurisdictions dealing with an outbreak of avian influenza and planning an investigation of possible human cases which may arise from an outbreak in birds. Other jurisdictions, not directly affected by the outbreak, are encouraged to refer to the sections of the Canadian Pandemic Influenza Plan that correspond to the pandemic phase (e.g., Canadian Phase 1.0 or 2.0) as indicated by the epidemiological findings from the outbreak. Suspect Case An individual presenting with onset of two or more of conjunctivitis*and/or H7N3 related influenza-like illness (ILI) symptoms** occurring between 1 day after first exposure/ contact and 7 days after last exposure/ contact inclusive, to a potential source of avian influenzavirus*** in the <geographic area>, <P/T>. Symptoms should not be fully attributable to another known etiology. *Conjunctivitis Symptoms:
**H7N3 related ILI Symptoms:
***Potential source of avian influenza can be:
Confirmed Case An individual who fulfills the criteria of a suspect case and has laboratory confirmation of influenza A (H7) virus in any specimen(s) from the eye (conjunctival swab), respiratory tract (nasal or nasopharyngeal swab or nasal wash) and/or serology by at least one of the following: 1) Virus isolation in cell culture 2) RT-PCR (confirmed by another RT-PCR test on a second specimen sample) 3) Evidence of sero-conversion from acute and convalescent sera, taken at a 2 week interval, with a four-fold rise in antibody titre. Asymptomatic or Atypical Infection: An individual who either has no clinical symptoms or has a clinical presentation unique from that of a suspect case yet has laboratory confirmation (i.e. as detailed above for a confirmed case) of an infection with influenza A (H7). Notes:
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Last Updated: 2006-10-25 | ![]() |