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Are spermicides safe and effective to use?


What are spermicides and how are they used?

Spermicides are chemical substances that kill sperm to protect against pregnancy. They come in many different forms including gels, foams, films, suppositories and lubricants. Spermicides are inserted into the vagina before intercourse. Spermicides should never be used for anal sex because they can irritate the lining of the anus.

Spermicides are most effective at preventing a pregnancy when they are used with another method of birth control such as a male condom, a female condom, a diaphragm or a cervical cap. Many brands of condoms also contain spermicides – it will say this on the package.  There are many different types of spermicidal products available at most drug stores in Canada and they do not require a prescription from a doctor.

Do spermicides protect against sexually transmitted infections (STIs)?

Spermicides do not provide reliable protection from many STIs. In fact, it’s been found that using spermicides that contain nonoxynol-9 may increase the risk of HIV and STI transmission.

What is nonoxynol-9?

Nonoxynol-9 (N-9) is a common chemical ingredient in spermicides. Researchers have found that N-9 may increase the risk of HIV and STI transmission because it can cause skin irritations, which may increase the risk of infection. You should avoid using a spermicide if you have any irritated areas.

Because of these findings, N-9 is not recommended as an effective way to prevent HIV. The best STI and HIV protection is a lubricated latex condom without N-9. However, a condom with N-9 is better than no condom at all. The protection you can get from a condom outweighs the risk of using the N-9.

Are spermicides and microbicides the same thing?

No. Spermicides are chemicals that kill sperm to protect against pregnancy. Microbicides are chemicals that kill viruses and bacteria to help protect against HIV and other STIs. Although there is research being done, right now there are no effective microbicides on the market and it’s not clear when that might happen. Nonoxynol-9, a common ingredient in spermicides, is not an effective microbicide. For more information on microbicides, see the FAQ, "What are microbicides?"

Additional resources

Alliance for Microbicide Development

Nonoxynol-9 and the risk of HIV transmissionPublic Health Agency of Canada

SpermicidesSunnybrook and Women's College Health Sciences Centre


Last Updated: 2007-08-01
Created for the Canadian Health Network by the Canadian Federation for Sexual Health.

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