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ealth
care is more than just doctors, nurses and patients. It also involves
researchers and policy makers. As Canada's premier federal funding
agency for health research, the Canadian Institutes of Health Research
(CIHR) brings together researchers from a variety disciplines to generate
new knowledge and then translate that knowledge into more effective
health services and products which strengthen the Canadian health
care system. Dr. Alan Bernstein, President of CIHR and a world renowned
geneticist, along with 19 Governing Council members, guide this vision
and help make it possible through CIHR's 13 "virtual" Institutes.
Each of these Institutes is dedicated to specific areas of research
in a coordinated effort to foster health research under four main
pillars. These pillars, which are dictated by CIHR's mandate, include:
biomedical research, clinical research, health systems and services,
and environmental, social and cultural determinants of health.
Biomedical studies apply the principles of the
natural sciences, especially biology and physiology, to clinical medicine.
For example, Dr. B. Brett Finlay, one of CIHR's Distinguished Investigators,
has developed a vaccine to protect cows against E. coli bacteria.
E. coli, responsible for "hamburger disease", causes
illness in thousands and kills 500 people each year. As a result,
federal government inspectors ordered zero tolerance toward beef cattle
that carry a particular strain of E. coli, (and cost meat producers
$5 billion per year). By attacking the direct cause in cows, Dr. Finlay
hopes to reduce the dramatic economic and health costs associated
with E. coli.
At CIHR, biomedical studies range from clinical
medicine to policies that concern research. This includes controversial
areas such as stem cell research. While stem cells have the potential
to treat a variety of diseases such as Parkinson's, diabetes, Alzheimer's
and heart disease, source derivation (embryonic versus adult stem
cells) raises many legal, social and ethical issues. Because there
is currently no legislation in Canada governing stem cell research,
CIHR introduced Human Pluripotent Stem Cell Research: Guidelines
for CIHR-funded Research. These guidelines, among many things,
assure Canadians that all federally-funded research projects will
adhere to an ethical and legal framework that does not allow human
embryonic stem cells to be used for cloning or commercial purposes.
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13 "virtual"
Institutes
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- Institute of Aboriginal
Peoples' Health,
- Institute of Aging,
- Institute of Cancer Research,
- Institute of Circulatory and Respiratory Health,
- Institute of Gender and Health,
- Institute of Genetics,
- Institute of Health Services and Policy Research,
- Institute of Human Development, Child, and Youth Health,
- Institute of Infection and Immunity,
- Institute of Musculoskeletal Health and Arthritis,
- Institute of Neurosciences, Mental Health and Addiction,
- Institute of Nutrition, Metabolism and Diabetes,
- Institute of Population and Public Health
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Clinical trials bring theory into practice. In
July 2002, CIHR and the federal government announced funding to the
first marijuana research study conducted in Canada. Led by five scientists
from different fields at McGill University, the study will examine
the prospective therapeutic uses of cannabis, the plant which produces
marijuana. The study will also be the world's first peer-reviewed
clinical trial examining the effects of smoked cannabis in a non-HIV
or Multiple Sclerosis population. The trial results will determine
the safety and efficacy of managing symptoms in patients who don't
respond to usual treatment - and eventually contribute to the development
of policies to address the medical use of marijuana and cannabinoids.
Health systems and services can always be improved to address the
needs of Canadians. CIHR's Institute of Aboriginal Peoples' Health
created the Aboriginal Capacity and Developmental Research Environments
(ACADRE), a program to facilitate health research by and for the Aboriginal
community across Canada. Given the unique health challenges faced
by Aboriginal people, the program has centers in Alberta, Saskatchewan,
Manitoba and Ontario to foster the growth of Aboriginal capacity in
health research.
The last area of research is population health, the environmental,
social and cultural factors affecting the health Canadians. CIHR can
respond to timely matters such as bioterrorism. In light of the Sept.
11, 2001 attacks and subsequent anthrax scares, CIHR's Institute of
Infection and Immunity and Health Canada co-sponsored an international
conference in Jan. 2002 entitled Biological Terrorism: Canadian
Research Agenda. The conference was focused on three areas: what
research contributions could Canadian scientists make, how Canada
could interact with international research efforts, and what specific
research initiatives could be recommended. Scientists, policy makers,
academics, public health organizers and military and industry personnel
from all across Canada attended the conference to set Canada's research
agenda in the face of bioterrorism.
In June 2002, Health Minister Anne McLellan and Dr. Bernstein announced
$88 million in funding for the Strategic Training Initiative in Health
Research . This funds 51 innovative transdisciplinary research projects
to train and support research talent (such as undergraduates, post-graduate,
post-doctoral and students in health professions such as nursing and
medicine).
It has been predicted that the 21st century will be the century of
health research. CIHR is a bold and innovative approach which will
ensure that Canada is a major player on the international stage. Based
on CIHR's four mandated pillars of research excellence, CIHR will
produce the greatest possible health outcomes for all Canadians.
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