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Notifiable Diseases On-Line

Hepatitis B (HBV) is an infection of the liver caused by the hepatitis B virus. The virus is spread by direct exposure to the blood or body fluids, such as semen, of those infected with HBV. Persons who inject drugs, who have a job that brings them into contact with blood or who have multiple sexual partners are at risk of exposure to HBV. As well, infected mothers can transmit the disease to their infants. Symptoms include loss of appetite, nausea and vomiting, stomach pain, fatigue and a yellowing of the skin and eyes (jaundice). Some people carry the virus for the rest of their lives after infection; these people may develop cirrhosis (scarring) of the liver, liver failure or liver cancer. HBV is preventable through immunization.

HEPATITIS B

AGENT OF DISEASE

Hepatitis B is caused by the hepatitis B virus (HBV), a hepadnavirus.

WORLDWIDE DISTRIBUTION

Hepatitis B occurs worldwide. In North America, infection occurs mainly in young adults. In Africa and Asia, HBV infection commonly occurs in infants and young children.

SYMPTOMS

Symptoms appear within 45 to 160 days (usually about 120 days) after exposure to HBV. The severity of the illness ranges from cases with no or mild symptoms to, uncommonly, severe cases that lead to liver failure. The number of cases with no or mild symptoms is high: only 10% of children and 30% to 50% of adults infected with HBV will have jaundice (yellowing of the skin and eyes). Other symptoms may include loss of appetite, stomach pain, nausea and vomiting, and occasionally joint pain and rash. Some people, especially infants and children, infected with HBV never completely recover and carry the virus in their blood for the rest of their lives. In some of these people there will be persistent inflammation of the liver and possibly cirrhosis (scarring and hardening) of the liver, liver failure and liver cancer.

PERIOD OF COMMUNICABILITY

The virus is in the blood several weeks before the onset of symptoms and remains there throughout the course of the infection. People who permanently carry the virus remain infectious to others.

HOW IT IS TRANSMITTED

Hepatitis B is spread through exposure to the blood or body fluids of those infected with the virus. A person can become infected with HBV from sexual contact with an infected person, sharing of injection equipment to inject drugs, transmission from an infected mother to her infant, or exposure to blood in the workplace. The risk of infection with HBV from a blood transfusion is very low in Canada because blood is screened for HBV.

PREVENTION/CONTROL

  1. HBV vaccine is now given routinely in most provinces and territories to young adolescents or to both infants and young adolescents.
  2. Hepatitis B vaccine is recommended for certain groups at higher risk of infection with HBV.
  3. Street drugs should not be injected. If they are, injection equipment must not be shared with others.
  4. Except in the case of an ongoing monogamous (one partner only) relationship, safer sex must be practised, e.g., reducing the number of sex partners, using a latex condom.
  5. Articles that might be contaminated with blood, e.g., toothbrushes, razors, must not be shared.

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Last Updated: 2003-12-11