Plague

    Overview

    Plague is an infectious disease caused by the bacteria Yersinia pestis, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacteriuma, it can also transmit from animals to humans.

    Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials, or by inhalation. Plague can be a very severe disease in people, particularly in its septicaemic and pneumonic forms, with a case-fatality ratio of 30% - 100% if left untreated.

    Although plague has been responsible for widespread pandemics throughout history, including the so-called Black Death that caused over 50 million deaths in Europe during the fourteenth century, today it can be easily treated with antibiotics and the use of standard preventative measures.

    Plague is found on all continents except Oceania but most human cases since the 1990s have occurred in Africa. Democratic Republic of Congo, Madagascar and Peru are the three most endemic countries.

     

    Symptoms

    Plague is an infectious disease caused by the bacteria Yersinia pestis, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacteriuma, it can also transmit from animals to humans.

    Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials, or by inhalation. Plague can be a very severe disease in people, particularly in its septicaemic and pneumonic forms, with a case-fatality ratio of 30% - –100% if left untreated.

    Although plague has been responsible for widespread pandemics throughout history, including the so-called Black Death that caused over 50 million deaths in Europe during the fourteenth century, today it can be easily treated with antibiotics and the use of standard preventative measures.

    Plague is found on all continents except Oceania but most human cases since the 1990s have occurred in Africa. Democratic Republic of Congo, Madagascar and Peru are the three most endemic countries.

    Treatment

    Plague is an infectious disease caused by the bacteria Yersinia pestis, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacteriuma, it can also transmit from animals to humans.

    Humans can be contaminated by the bite of infected fleas, through direct contact with infected materials, or by inhalation. Plague can be a very severe disease in people, particularly in its septicaemic and pneumonic forms, with a case-fatality ratio of 30% - –100% if left untreated.

    Although plague has been responsible for widespread pandemics throughout history, including the so-called Black Death that caused over 50 million deaths in Europe during the fourteenth century, today it can be easily treated with antibiotics and the use of standard preventative measures.

    Plague is found on all continents except Oceania but most human cases since the 1990s have occurred in Africa. Democratic Republic of Congo, Madagascar and Peru are the three most endemic countries.

    Country readiness checklist (in English)

    Country readiness checklist (in French)

    Country readiness checklist (in Portugese)

    3 - 7 days

    incubation period

    The case-fatality ratio of 30%-100% if left untreated

    Untreated plague

    can be rapidly fatal