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Peer Review Committees and Mandates

The following table presents an alphabetized list of peer review committees and their corresponding mandates, for the CIHR Operating Grants Program. When applying for funding, you should suggest up to two peer review committees whose mandates most closely align with your research project. Note that many of the peer review committee mandates have recently been revised. Please review the committee mandates before applying in order to correctly identify the best committees to review your application.

If you require more information in order to suggest an appropriate peer review committee, you may query the CIHR Funding Database by research subject, to see which committees reviewed projects similar to yours. The detailed list of query results includes information on the project title, assigned peer review committee, abstract, amount of funds awarded and period of funding.

Committee Examples of Research Covered CIHR Contact
Aboriginal Peoples' Health (ABH) Disciplinary and interdisciplinary approaches to aboriginal health research. Ethical, cultural, mental, physical, social, psychological, spiritual, environmental, genetic determinants and/or aspects of illness and wellness in aboriginal populations. Aboriginal Health services, policy development and knowledge translation. Aboriginal world view of health and well-being that includes balancing mental, physical, spiritual and emotional aspects; investigating indigenous knowledge, traditional medicine, spiritual health.

The committee reviews applications using the full range of relevant disciplinary methodologies, with an emphasis on the integration of advanced health research methods with community-based approaches, multi-sectoral partnership models, participatory action research, and indigenous methodologies. Investigations that contribute to capacity-building for both the advanced health research community and aboriginal populations are encouraged. Community capacity-building encouraged by the Committee could include, but not be limited to: inclusion of a community member on the research team, hiring of community-based research assistants, establishing a Community Advisory Group and describing its role throughout the duration of the research process, inclusion of community-based dissemination strategies for research findings, signing of a research protocol with participating communities, involvement of community members in development of a program-based intervention and including a sustainability plan for the intervention once the research is completed.

Research with aboriginal communities outside of Canada must clearly demonstrate how the research and the research results will benefit Canadian aboriginal populations.
DG
Behavioural Sciences - A (BSA) Basic behavioural studies (usually in animals) investigating mechanisms of psychiatric or neurological disorders, motivation, reinforcement, ingestive behaviour, drug self-administration, learning, neuroplasticity, neurodegeneration/neuroprotection, recovery of function, circadian rhythms, stress, epilepsy; the genetic bases of behaviour; neuro- and behavioural pharmacology; neuro- and behavioural endocrinology; neuro- and behavioural immunology; and related research. Methodologies used include but are not restricted to behavioural testing, lesions, electrophysiological recordings, drug administration, biochemical assays, imaging, genetic analyses and manipulations, molecular biology techniques, etc. NG
Behavioural Sciences - B (BSB)
(Clinical Behavioural Sciences)
Clinical/applied studies in psychiatric or neurologic populations of ADHD, schizophrenia, bipolar disorder, anxiety, depression, mood disorders, personality disorders, autism, intellectual disabilities, obsessive-compulsive disorder, alcohol and/or drug addiction, and other psychiatric or behavioural conditions; neuropsychiatry/neuropsychology; behavioural neurology. Methodologies used include but are not restricted to behavioural testing, imaging, genetic analyses, biochemical assays, electrophysiological recordings, drug administration, etc. NG
Behavioural Sciences - C (BSC)
(Behavioural Studies and Neural Imaging)
Basic studies, using cognitive, systems, or behavioural neuroscience approaches (in humans or animal models), of cognition, attention, memory, sensory and motor functions/integration, perception, sleep, pain, speech/language; neuropsychology. Methodologies used include but are not restricted to behavioural testing, psychophysics, electrophysiological recordings, imaging, molecular/cellular techniques, neuroanatomy, gait studies, eye movement recordings, computational neuroscience, etc. NG
Biochemistry & Molecular Biology - A (BMA) Structural biology. Biophysical investigations of macromolecules. Membrane proteins and/or bioenergetics (including relevant lipids). Enzymology and enzyme mechanisms. MH
Biochemistry & Molecular Biology - B (BMB) Protein and nucleic acid molecular biology. Gene expression. Transcription. Translation.

Note: Studies with a primarily developmental focus should be referred to the committee on Development (DEV).
MH
Biological & Clinical Aspects of Aging (BCA) Cellular mechanisms of aging, cell senescence, cellular response to stress. Longevity genes and senescence genes. Mechanisms of exceptional aging, premature aging syndrome. Animal models of aging. Predictive markers of biological health and aging. Molecular and cellular basis of age-related changes in tissues and systems (e.g., osteoporosis and osteoarthritis, age-related decline in immune function, changes in sleep and biological rhythms). Causes, prevention, and treatment of geriatric syndromes, including falls, frailty and functional decline, immobility, delirium, incontinence. Management of chronic pain. Cognitive decline in the elderly. ML
Biomedical Engineering (BME) Medical devices including prosthetic devices and artificial organs. Organ and tissue preservation. Biological application of physical methods. Numerical models of physiological systems. Computer applications. Biomaterials. Biomechanics. Regenerative medicine, skin and tissue engineering, bladder and bone repair and regeneration.

Note: Gait studies, biomechanical studies dealing with movement, studies with a focus on rehabilitation for movement disorders, should be referred to the committee on Movement and Exercise (MOV).
RS
Cancer Biology & Therapeutics (CBT) Carcinogenesis. Basic and translational aspects of DNA repair, cell cycle/checkpoints, vaccine, and gene therapy. Radiation biology. Experimental radiotherapy. Cancer immunotherapy. Innovative tumour markers. Cancer prevention approaches. MH
Cancer Progression & Therapeutics (CPT) Cancer progession biomarkers, including angiogenesis and host/tumour microenvironment modifications. Development of innovative pharmacological agents and targets. Molecular targeting therapies. Exploratory translational cancer research. Molecular epidemiology of innovative tumour markers. MH
Cardiovascular System - A (CSA)
(Cells & Tissues)
Research on the heart at the levels of tissues and cells: electrophysiology, metabolism, molecular biology, cardiac muscle, cell biology. Genetic studies, ion channels, molecular signaling in cardiology, cardiac development, and cardiac tissue cell culture. NG
Cardiovascular System - B (CSB)
(Whole Organisms)
Physiological studies. Research on the heart at the level of the whole organism, or the organ: hemodynamics, hypertension, myocardial protection, cardiac remodeling, myocardial ischemia and reperfusion, neuro- and endocrine regulation. Studies of animal models of human cardiac disease, cardiovascular clinical pathophysiology and therapeutics. Genetic models of heart failure. NG
Cardiovascular System - C (CSC)
(Vascular System)
Research on the vascular system, including the endothelium, with an emphasis on the cellular, molecular, and immune mechanisms that regulate cardiovascular function in normal and disease states. Atherosclerosis, inflammation, and thrombosis. NG
Cell Biology & Mechanisms of Disease (CBM) Morphological studies, including structure/function relationships. Cellular and experimental pathology.

Note: Studies on developmental biology, embryology, or teratology should be referred to the committee on Development (DEV).
ML
Cell Physiology (CP) Signal transduction. Cytoskeleton. Cell cycle. Differentiation. Ion channels. Bioenergetics. Membrane structure and function. Transport mechanisms. Secretion mechanisms.

Note: Studies dealing with muscle contraction should be referred to the committee on Movement and Exercise (MOV).
MH
Children's Health (CHI) Conditions for optimizing child development. Prevention, treatment, and strategies for support of children with physical, mental, and behavioural health challenges. Birth defects, congenital abnormalities, the effects of environmental toxins on reproductive and child health. Life style and social influences on fetal, maternal, and neonatal health. Health impacts and outcomes of family dynamics and childcare; parenting; attachment patterns; impacts of poverty; violence and abuse. Specific childhood and youth-related conditions: causal factors, prevention, early identification, treatment, and long-term management, with consideration of school-related issues and issues related to the official language minority status.

Note also that randomized controlled trials must be submitted to the Randomized Controlled Trials Program.
ML
Clinical Investigation - A (CIA) Paediatrics. Obstetrics and gynaecology. Neonatology. Perinatology. Ophthalmology. Otolaryngology. Radiology. Anaesthesia.

Note: Studies dealing with child development, birth defects, environmental and social impacts on children's health, should be referred to the committee on Children's Health (CHI).


Note also that randomized controlled trials must be submitted to the Randomized Controlled Trials Program.
ML
Clinical Investigation - B (CIB)
(Arthritis, Bone and Cartilage)
Dermatology. Arthritis and joint disease. Rheumatology. Orthopaedics. Skin and wound healing. Bone and mineral metabolism.

Note also that randomized controlled trials must be submitted to the Randomized Controlled Trials Program.
RS
Dental Science (DS) Studies of structure and function in health and disease of tissues in the oral cavity and craniofacial structures. Research on the craniofacial and oral health cavity with an emphasis on the developmental, cellular, molecular, genetic and immune mechanisms that regulate oral function in normal and disease states. This includes oral microbiology, epidemiology and public health, biomaterials, orofacial neurophysiology and related treatment. RS
Developmental Biology (DEV) Molecular genetics of development, control of gene expression during development. Cell interactions and cell-matrix interactions. Pattern formation, cell determination and differentiation, specification of tissue type, targeted disruptions of developmental control genes, the roles of transcription factors and growth factors in development, regulatory hierarchies of gene expression, cell-cell communication and signal transduction in development, post-transcriptional controls of developmental processes such as regulated splicing and protein modification. Regulation and differentiation of stem cell populations. Developmental neurobiology. Morphogenesis, embryology, teratology, stem cell biology. ML
Endocrinology (E) Peptide and polypeptide hormone biosynthesis/processing and receptors. Steroid and thyroid hormone synthesis/metabolism, binding proteins and nuclear hormone receptors. Hormone signaling pathways and regulation of target genes. Mechanisms of hormone action and endocrine disruption. Development and/or differentiation of endocrine cells. Cellular and molecular biology of endocrine organs/tissues. Male and female reproductive endocrinology, and hormonal basis of fertility control and infertility. Gonads and the hormonal control of gametogenesis. Developmental endocrinology. Pregnancy and parturition. Puberty and aging. Neuroendocrinology. Hormones and cancer. Endocrine basis of metabolic/cardiovascular diseases. Biochemical and genetic/molecular basis of endocrinopathies. NG
Health Ethics, Law, & Humanities (ELH) Systematic analyses of values and ethical theory as applied in health care, health research, and new health technologies. Individual and property rights related to health technologies and treatments, health law. Ethical issues associated with population screening, privacy and use of genetic and other database information, community and population-based risk management strategies. Ethical aspects of research using human embryos, and new reproductive technologies. Informed consent. Research on collectivities.

Note: Studies dealing with the humanities as applied to health issues should be referred to the committee on Humanities Perspectives on Health (HUP).
DG
Experimental Medicine (EM) Cellular physiology and molecular biology with a focus on disease in the following systems: haematology, gastroenterology, nephrology, urology, and hepatology. NG
Gender, Sex, & Health (GSH) How sex (i.e., biological factors) and gender (i.e., sociocultural conditions/experiences) influence health status, health behaviour, and health services use. The interaction of sex and gender with other determinants of health (e.g., income, education, culture, official language minority status, ability, environment, geography). Sex differences and gender influences, alone or in combination/interaction with other factors, on the health of females and males across the life span. Research designed to test relevant interventions.

Applicants are encouraged to demonstrate the use of gender and sex-based analysis (GSBA) in their applications. To learn more about GSBA, please refer to the CIHR Grants and Awards Guide.
DG
Genetics (G) Inherited disease and disease susceptibility; mutation and mutational mechanisms; modeling of human genetic disease; genotypes, phenotypes and natural history of genetic disease; metabolic genetics; population and statistical genetics; cytogenetics; epigenetic inheritance and gene regulation; genetics of DNA repair, replication and recombination; gene and gene based therapies. MH
Genomics (GMX) Genome mapping and sequencing. Functional genomics. Genotyping technologies. Proteomics. Bioinformatics. MH
Health Services Evaluation & Interventions Research - A and B (HSR and HSI) Effectiveness and efficiency of health services at the individual, community, and population levels. Research into the delivery of all health services, including improving access to care for disadvantaged populations (e.g. official language minority communities, rural/northern residents, etc.). Evidenced based practice. Care provider issues. Primary care, home care, quality of care, effectiveness, efficiency, and equity of interventions, and delivery of health services given by health professionals and others.

Notes: Applicants should also read the mandate of the committee on Knowledge Translation and Exchange (KTE). Studies in which the primary focus is on children, the elderly, or gender issues should be referred to the committees on Children's Health (CHI), Social Dimensions in Aging (SDA), or Gender, Sex, and Health (GSH).


Note also that randomized controlled trials must be submitted to the Randomized Controlled Trials Program.
RS
Health Policy & Systems Management Research (HPM) Application of social science disciplines and methods to the study of the health care system. Health policy and politics. Health economics, including economic evaluation (when it is the primary focus of the proposal); analysis of financing, funding, and remuneration methods; and analysis of resource allocation mechanisms. Health systems management, including perspectives like health administration, organizational behaviour, management science, and health systems analysis; and topics like governance, integrated health systems, and managed care. Health human resources, including the structure and organization of health professions and nursing research, and the availability of appropriate health professionals to provide necessary services to disadvantaged populations (e.g. official language minority communities, rural/northern residents, aboriginal populations, etc.).

Notes: Studies in which the primary focus is on children, the elderly, or gender issues should be referred to the committees on Children's Health (CHI), Social Dimensions in Aging (SDA), or Gender, Sex, and Health (GSH).
RS
Humanities Perspectives on Health (HUP) 1. Conceptual and Historical Analyses of what it means to be a healthy human being in various cultures/religious/linguistic traditions and the implications that has for:
(a) conceptions of health and illness, life and death
(b) the ethics of health care
(c) the education of health care professionals
(d) the provision of health care
(e) decision-making around health research agendas and technical innovations
(f) the concepts of civic mindedness and public good
(g) the sense of self and identity.

2. Contributions of literature and literary studies to various understandings of health and health care:
(a) use of narrative in the analysis of health experiences
(b) the role of metaphor in the interdisciplinary and public understanding of health and health care.

3. Contributions of the performing and visual arts to health and health care.

4. In light of new technologies and of unfolding social and cultural paradigms, what contributions can humanists make to the question of Nurture and Nature in health and health care that bear on public policy.
DG
Immunology & Transplantation (IT) Cellular immunology and transplantation. Synthesis of antibodies. Immunogenetics. Immunosuppression and tolerance. Cell-to-cell interactions. Lymphokines. Autoimmunity. Allergy. Mediators of inflammation. Immunoglobulins and IG genes. Molecular immunology. Mucosal immunity. IJ
Knowledge Translation & Exchange (KTE) Consumer health information, practice guideline development and uptake, systematic reviews, investigations into determinants of uptake of research evidence by policy-makers. Dissemination and uptake of information. New technologies for health information dissemination. Public expectations of the health care and health research systems. Best practices in engaging public debate on health research and health care delivery. Research in education relating to health professionals and practice. DG
Medical Physics & Imaging (MPI) Development and application of physical methods in medicine and biology including imaging methods, computer applications, radiation therapy and radiation biophysics. RS
Metabolism (M) Lipid metabolism including lipoproteins. Carbohydrate metabolism. Connective tissue metabolism. Metabolic aspects of nutrition, obesity and diabetes. Energy metabolism.

Note: Studies dealing with human nutrition, prevention and education of obesity and diabetes, or the relation between diet and health should be referred to the committee on Nutrition, Food, and Health (NUT).
NG
Molecular & Cellular Biology of Cancer (MCC) Mechanistic analysis of cancer etiology and discovery research relating to fundamental tumourigenic processes such as angiogenesis, cell cycle/proliferation, stem cell fate/differentiation, growth regulation, apoptosis and metastasis. Includes studies of gene expression, signal transduction, cancer genomics and use of model organism and molecular genetic approaches. MH
Microbiology & Infectious Diseases (MI) Parasitology. Immunology as related to microorganisms. Epidemiology, diagnosis and therapy of infectious diseases. Antimicrobial resistance. Macrophage biology. Virulence factors. IJ
Movement & Exercise (MOV) Gait studies, biomechanics. Muscle biology, fibre typing and regulation. Muscle contraction. Movement disorders, neuromuscular disorders, myopathies. Sensory motor integration. Exercise physiology, role of exercise in health promotion and rehabilitation. Rehabilitation and physical therapy. Orthopaedics applied to the articular system. Occupational ergonomics. Kinesiology. Health and physical fitness. RS
Neurosciences - A and B (NSA and NSB) Neural cell biology. Neuroanatomy. Neurochemistry. Molecular neurobiology. Autonomic nervous system. Neuropathology. Neurology. Neuroimmunology. Developmental neurobiology. Motor and sensory systems and associated disorders. Integrated neurosciences. ANS and CNS transmitters. Regulatory neurosciences including neuroendocrinology.

Notes: Studies of neural development with a molecular or cellular focus should be referred to the committee on Development (DEV). Studies dealing with muscle, myopathies, biomechanics, kinesiology, and exercise should be referred to the committee on Movement and Exercise (MOV).
NG
Nutrition, Food, & Health (NUT) Human nutrition through the life span. Dietetics. Obesity, including evaluations of new glucose and weight-lowering drugs. Energy balance and nutrition. Health consequences of specific diets and dietary supplements, nutritional factors in the etiology of metabolic and gastrointestinal disorders, the epidemiological association between dietary habits and disease incidence. Food intolerance and allergy. Nutrition-related education and health promotion. Diabetes prevention and education. The influence of socioeconomic, cultural, and political factors on nutrition of the individual and the community. The impact of nutrient intake on disease response, work performance, and behaviour. Population and life cycle nutrient use and requirements. Pathogenesis of nutrient imbalance. Non-oral feeding strategies. Food production techniques and food handling, food and water safety. Probiotics. Nutrigenetics and nutrigenomics. NG
Palliative & End of Life Care (PLC) Epidemiological studies and surveys of problems related to palliative and end of life care; the development of methods for the early detection, prevention and management of suffering associated with life-limiting illness and prolonged morbidity resulting from any disease; studies on medical, physical, psychosocial and spiritual approaches to the minimization of pain and other symptoms for both patients and families; training for families and other caregivers in innovative communication and decision-making processes; health services research, including the development of novel methods and tools; the promotion of knowledge translation through informed policies and clinical practices aimed at improving the quality and dignity of life for the patients. The committee will also review proposals that address critical evaluation of ethical, legal, economic and moral issues pertaining to the utilization of health care resources and the quality of care. MH
Pharmaceutical Sciences (PS) Drug delivery. Drug design. Medicinal chemistry, radio-pharmaceuticals, biopharmaceutics and drug analyses. Pharmacognosy and pharmacokinetics. IJ
Pharmacology & Toxicology (PT) Drug metabolism. Toxicology. Drug abuse and addiction. Mechanisms of drug action. Characterization of drug targets. Pharmacology of biological substances. Clinical pharmacology. Pharmacogenetics. IJ
Psychosocial, Sociocultural, & Behavioural Determinants of Health - A and B (PSB and PSD) Behavioural and social science research applied to health, health behavior, quality of life, psychophysiology, and community health including, but not limited to, hypothesis-testing and clinically applied projects. Behavioural, social, and cultural factors, including disadvantaged populations' status (e.g. official language minority communities, rural/northern residents, etc.) as they relate to health, disease, and biomedical treatments. Individual and population perspectives can be adopted. Projects address these issues from the perspective of the social, health professional and behavioural sciences, emphasizing a priori hypotheses, prospective designs, and psychometric measurement criteria as well as qualitative studies.

Notes: Studies with a primary focus on child development, familial, parental and social influences on the health of children should be referred to the committee on Children's Health (CHI). Studies with a primary focus on the elderly should be referred to the committee on Social Dimensions in Aging (SDA). Studies where gender issues are a primary focus should be referred to the committee on Gender, Sex, and Health (GSH). Studies dealing with questions of human values in health care contexts should be referred to the committee on Humanities Perspectives on Health (HUP).


Because PSB and PSD have the same mandate, applications may be transferred between the two committees based on expertise and conflicts of interest. Applicants are therefore discouraged from indicating both PSB and PSD as their first and second committee choices as this would effectively count for only one choice.
DG
Public, Community, & Population Health - A and B (POP and PUB) The conception and measurement of exposures and health status and the testing of hypotheses concerning exposure/disease relationships. The mandate includes the development or application of novel statistical methods. Research on the etiology of human disease and disability. The measurement of burden of disease in populations, ranging from gene/environment interactions in the biological origins of disease to the impact of social environments, including disadvantaged populations' status (e.g. official language minority communities, rural/northern residents, etc.), on health and functional status. Work and health. Health inequalities and gradients. Health of diverse and disadvantaged populations. Food and water safety. Impact of global change on health.

Notes: Studies with a primary focus on child development, familial, parental, and social influences on the health of children, should be referred to the committee on Children's Health (CHI). Studies with a primary focus on the elderly should be referred to the committee on Social Dimensions in Aging (SDA). Studies where gender issues are a primary focus should be referred to the committee on Gender, Sex, and Health (GSH). Studies with a focus on nutrition or food safety should be referred to the committee on Nutrition, Food, and Health (NUT).
RS
Randomized Controlled Trials A randomized controlled trial (RCT) is an experiment in which investigators randomly assign eligible subjects (or other units of study; e.g., classrooms, clinics, playgrounds) into groups to receive or not receive one or more interventions that are being compared. The results are analyzed by comparing outcomes in the groups.

Note: RCTs must be submitted to the Randomized Controlled Trials Program which has requirements and timelines that are different from the Operating Grant Program.
IS
Respiratory System (RS) Destructive and obstructive lung disease. Lung mechanics. Pulmonary circulation. Sleep-related disorders. Lung and associated tissue. Respiratory diseases of the newborn. Nonmicrobial diseases of the adult. Surfactant. Respiratory control mechanisms. Airway smooth muscle. Neurocontrol of breathing. NG
Social Dimensions in Aging (SDA) Social factors as determinants of health and quality of life in aging (e.g., social support, work, participation of the elderly persons in society, leisure and recreation, household and family structure, housing, transportation, economic status and inequality, retirement). Positive health behaviours, and healthy life styles, physical activity. Life-course interactions and transitions. Long-term care and caregiving for the elderly, including assisted or supportive living facilities, care at home. Health services for the elderly, including those living in rural, northern, and official language minority communities. Palliative care: pain management, individual and family support, choice of settings and implications of choices, strategies for implementing end-of-life guidelines. Health status of the elderly population. Studies of social factors affecting specific age-related physical, cognitive, communications, behavioural, and mental health problems. Elder abuse and neglect. ML
Virology & Viral Pathogenesis (VVP) Virology. Immunology as related to viruses. Epidemiology, diagnosis and therapy of viral diseases. Antiviral resistance. IJ

Key to CIHR contacts:

IJ Dr. Isabelle Jalbert (effective August 21, 2006)
Tel: (613) 941-3579
E-mail: ijalbert@cihr-irsc.gc.ca
IS Ms. Isabelle Schmid
Tel: (613) 954-6643
E-mail: ischmid@cihr-irsc.gc.ca
DG Dr. Daniel Guerin (effective August 1, 2006)
Tel: (613) 954-0582
E-mail: dguerin@cihr-irsc.gc.ca
MH Dr. Mohammed Hannan
Tel: (613) 954-5320
E-mail: mhannan@cihr-irsc.gc.ca
ML Dr. Martine Lafrance
Tel: (613) 941-4643
E-mail: mlafrance@cihr-irsc.gc.ca
NG Dr. Nathalie Gendron
Tel: (613) 941-4576
E-mail: ngendron@cihr-irsc.gc.ca
RS Dr. Richard Snell
Tel: (613) 954-7224
E-mail: rsnell@cihr-irsc.gc.ca
Fax: (613) 954-1800

Updated 2006/07/18


Created: 2003-04-17
Modified: 2006-09-13
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