As a singer/songwriter, Obomsawin has toured Canada, the United States and Europe performing for humanitarian causes in universities, museums, prisons and art centres, as well as at folk art festivals. Her 1988 album Bush Lady features traditional songs of the Abenaki people, as well as original compositions.

For over 25 years, Obomsawin has worked as an engraver and print-maker, with exhibitions in Canada and Europe. Mother and child imagery is prominent in her work, which also combines material from her own dreams with animal spirits and historical events. Her work was exhibited at the Maison Lacombe in Quebec in 2007.